| Title: | A multi-species bait for Chagas disease vectors |
| Author(s): | Mota T; Vitta AC; Lorenzo-Figueiras AN; Barezani CP; Zani CL; Lazzari CR; Diotaiuti L; Jeffares L; Bohman B; Lorenzo MG; |
| Address: | "Laboratorio de Triatomineos e Epidemiologia da Doenca de Chagas, CPqRR-FIOCRUZ, Belo Horizonte, Brazil ; Departamento de Fisiologia e Biofisica, Instituto de Ciencias Biologicas-UFMG, Belo Horizonte, Brazil. Laboratorio de Triatomineos e Epidemiologia da Doenca de Chagas, CPqRR-FIOCRUZ, Belo Horizonte, Brazil. Laboratorio de Fisiologia de Insectos, IBBEA-CONICET, FCEyN, Universidad de Buenos Aires, Buenos Aires, Argentina. Laboratorio de Quimica de Produtos Naturais, CPqRR-FIOCRUZ, Belo Horizonte, Brazil. Institut de Recherche sur la Biologie de l'Insecte, UMR CNRS 7261, Universite Francois Rabelais, Tours, France" |
| DOI: | 10.1371/journal.pntd.0002677 |
| ISSN/ISBN: | 1935-2735 (Electronic) 1935-2727 (Print) 1935-2727 (Linking) |
| Abstract: | "BACKGROUND: Triatomine bugs are the insect vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. These insects are known to aggregate inside shelters during daylight hours and it has been demonstrated that within shelters, the aggregation is induced by volatiles emitted from bug feces. These signals promote inter-species aggregation among most species studied, but the chemical composition is unknown. METHODOLOGY/PRINCIPAL FINDINGS: In the present work, feces from larvae of the three species were obtained and volatile compounds were identified by solid phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS). We identified five compounds, all present in feces of all of the three species: Triatoma infestans, Panstrongylus megistus and Triatoma brasiliensis. These substances were tested for attractivity and ability to recruit insects into shelters. Behaviorally active doses of the five substances were obtained for all three triatomine species. The bugs were significantly attracted to shelters baited with blends of 160 ng or 1.6 microg of each substance. CONCLUSIONS/SIGNIFICANCE: Common compounds were found in the feces of vectors of Chagas disease that actively recruited insects into shelters, which suggests that this blend of compounds could be used for the development of baits for early detection of reinfestation with triatomine bugs" |
| Keywords: | "Animals Behavior, Animal/drug effects Chagas Disease/*prevention & control Feces/*chemistry Insect Control/*methods *Insect Vectors/drug effects/physiology Larva Panstrongylus/drug effects/physiology Pheromones *Triatoma/drug effects/physiology Volatile O;" |
| Notes: | "MedlineMota, Theo Vitta, Ana C R Lorenzo-Figueiras, Alicia N Barezani, Carla P Zani, Carlos L Lazzari, Claudio R Diotaiuti, Lileia Jeffares, Lynne Bohman, Bjorn Lorenzo, Marcelo G eng Research Support, Non-U.S. Gov't 2014/03/04 PLoS Negl Trop Dis. 2014 Feb 27; 8(2):e2677. doi: 10.1371/journal.pntd.0002677. eCollection 2014 Feb" |
