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J Breath Res

Title:		Persistence of aroma volatiles in the oral and nasal cavities: real-time monitoring of decay rate in air exhaled through the nose and mouth
Author(s):		Sanchez-Lopez JA; Ziere A; Martins SI; Zimmermann R; Yeretzian C;
Address:		"Zurich University of Applied Sciences, Institute of Chemistry and Biotechnology, 8820 Wadenswil, Switzerland. Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry, University of Rostock, D-18059 Rostock, Germany"
Journal Title:		J Breath Res
Year:		2016
Volume:		20160706
Issue:		3
Page Number:		36005 -
DOI:		10.1088/1752-7155/10/3/036005
ISSN/ISBN:		1752-7163 (Electronic) 1752-7155 (Linking)
Abstract:		"The persistence of aroma compounds in breath after swallowing is an important attribute of the overall aroma experience during eating and drinking. It is mainly related to the coating of the oral tract with food residues and the interaction between volatile compounds and airway mucosa. We have studied the persistence of eight compounds (2,5-dimethylpyrazine, guaiacol, 4-methylguaiacol, phenylethylalcohol, ethylbutanoate, ethyloctanoate, isoamylacetate and 2-heptanone) both in-nose and in-mouth after administration of volatiles in gas phase (vapor) to five different panelists. By using volatiles in the gas phase, only the interaction with the mucosa is highlighted and the formation of a liquid coating in the oral and tracheal airway is avoided. The physicochemical properties of the compounds, mainly polarity and vapor pressure, determine the interactions of the volatiles with the airway mucosa. The use of different breathing protocols allowed the study of the differences between nasal and oral mucosa in volatile retention, with higher persistence of volatiles obtained in-mouth. Initial concentration also affected persistence, but only for compounds with high volatility and at low concentration"
Keywords:		Adult Breath Tests/*methods *Computer Systems *Exhalation Female Humans Male Mass Spectrometry Middle Aged Mouth/*chemistry Nasal Cavity/*chemistry Nose Odorants/*analysis Volatile Organic Compounds/*analysis;
Notes:		"MedlineSanchez-Lopez, Jose Antonio Ziere, Aldo Martins, Sara I F S Zimmermann, Ralf Yeretzian, Chahan eng Clinical Trial Research Support, Non-U.S. Gov't England 2016/07/07 J Breath Res. 2016 Jul 6; 10(3):036005. doi: 10.1088/1752-7155/10/3/036005"