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« Previous Abstract"Sources, concentrations, and exposure effects of environmental gestagens on fish and other aquatic wildlife, with an emphasis on reproduction"    Next AbstractSaccharomyces cerevisiae mating pheromones specifically inhibit the synthesis of proteins destined to be N-glycosylated »

FEBS Lett


Title:Saccharomyces cerevisiae alpha-factor prevents formation of glycoproteins in a cells
Author(s):Orlean P; Seebacher G; Tanner W;
Address:
Journal Title:FEBS Lett
Year:1983
Volume:158
Issue:2
Page Number:247 - 251
DOI: 10.1016/0014-5793(83)80588-2
ISSN/ISBN:0014-5793 (Print) 0014-5793 (Linking)
Abstract:alpha-Factor inhibits incorporation of [14C]glucosamine into water-soluble and into SDS-extractable glycoproteins to about 90%. The incorporation into chitin is not affected and the same is true for [14C]phenylalanine incorporation into protein. The inhibition of glycoprotein synthesis is specific for a cells
Keywords:Glucosamine/metabolism Glucose/metabolism Glycoproteins/*biosynthesis Mannose/metabolism Mating Factor Peptides/*pharmacology Phenylalanine/metabolism Saccharomyces cerevisiae/*metabolism Solubility;
Notes:"MedlineOrlean, P Seebacher, G Tanner, W eng Research Support, Non-U.S. Gov't England 1983/07/25 FEBS Lett. 1983 Jul 25; 158(2):247-51. doi: 10.1016/0014-5793(83)80588-2"

 
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