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Nat Neurosci

Title:		Suppression of male courtship by a Drosophila pheromone receptor
Author(s):		Miyamoto T; Amrein H;
Address:		"Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA"
Journal Title:		Nat Neurosci
Year:		2008
Volume:		20080720
Issue:		8
Page Number:		874 - 876
DOI:		10.1038/nn.2161
ISSN/ISBN:		1546-1726 (Electronic) 1097-6256 (Print) 1097-6256 (Linking)
Abstract:		"In male Drosophila, chemosensory cues control many aspects of social behavior. We found that males with a mutated Gustatory receptor 32a gene (Gr32a) show high courtship toward males and mated females, indicating that GR32a functions as a pheromone receptor for a male inhibitory pheromone. Notably, we discovered that tarsal Gr32a-expressing neurons were essential for courtship suppression and projected to the ventrolateral protocerebrum, implying direct communication of chemosensory neurons with a higher-order brain structure"
Keywords:		"Animals Animals, Genetically Modified *Courtship Drosophila Proteins/genetics/*physiology Drosophila melanogaster/genetics/*physiology Extremities/innervation Female Gene Targeting *Inhibition, Psychological Male Neurons/physiology Receptors, Cell Surface;"
Notes:		"MedlineMiyamoto, Tetsuya Amrein, Hubert eng R01 DC005606/DC/NIDCD NIH HHS/ R01 DC009014/DC/NIDCD NIH HHS/ 01DC005606/DC/NIDCD NIH HHS/ 01DC009014/DC/NIDCD NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't 2008/07/22 Nat Neurosci. 2008 Aug; 11(8):874-6. doi: 10.1038/nn.2161. Epub 2008 Jul 20"