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Nucleosides Nucleotides Nucleic Acids

Title:		Phylogenetic Analysis of Selected Menthol-Producing Species Belonging to the Lamiaceae Family
Author(s):		Mirzaei M; Mirzaei H; Sahebkar A; Bagherian A; Masoud Khoi MJ; Reza Mirzaei H; Salehi R; Reza Jaafari M; Kazemi Oskuee R;
Address:		"a Department of Biology , Faculty of Basic Sciences, University of Golestan , Gorgan , Iran"
Journal Title:		Nucleosides Nucleotides Nucleic Acids
Year:		2015
Volume:		34
Issue:		9
Page Number:		650 - 657
DOI:		10.1080/15257770.2015.1047030
ISSN/ISBN:		1532-2335 (Electronic) 1525-7770 (Linking)
Abstract:		"Menthol is an organic compound with diverse medicinal and commercial applications, and is made either synthetically or through extraction from mint oils. The aim of the present study was to investigate menthol levels in selected menthol-producing species belonging to the Lamiaceae family, and to determine phylogenetic relationships of menthol dehydrogenase gene sequence among these species. Three genus of Lamiaceae, namely Mentha, Salvia, and Micromeria, were selected for phytochemical and phylogenetic analyses. After identification of each species based on menthol dehydrogenase gene in NCBI, BLAST software was used for the sequence alignment. MEGA4 software was used to draw phylogenetic tree for various species. Phytochemical analysis revealed that the highest and lowest amounts of both essential oil and menthol belonged to Mentha spicata and Micromeria hyssopifolia, respectively. The species Mentha spicata and Mentha piperita, which were assigned to one cluster in the dendrogram, contained the highest amounts of essential oil and menthol while Micromeria species, which was in the distinct cluster and placed in the farther evolutionary distance, contained the lowest amount of essential oil and menthol. Phylogenetic and phytochemistry analyses showed that essential oil and menthol contents of menthol-producing species are associated with menthol dehydrogenase gene sequence"
Keywords:		"Genes, Plant Lamiaceae/chemistry/*classification/*genetics/metabolism Menthol/chemistry/metabolism Oils, Volatile/chemistry/metabolism *Phylogeny Lamiaceae menthol phylogeny phytochemistry volatile oil;"
Notes:		"MedlineMirzaei, Motahareh Mirzaei, Hamed Sahebkar, Amirhossein Bagherian, Ali Masoud Khoi, Mohammad Jaber Reza Mirzaei, Hamid Salehi, Rasoul Reza Jaafari, Mahmoud Kazemi Oskuee, Reza eng 2015/08/08 Nucleosides Nucleotides Nucleic Acids. 2015; 34(9):650-7. doi: 10.1080/15257770.2015.1047030"