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J Agric Food Chem

Title:		Simultaneous quantitation of multiple classes of organohalogen compounds in fish oils with direct sample introduction comprehensive two-dimensional gas chromatography and time-of-flight mass spectrometry
Author(s):		Hoh E; Lehotay SJ; Pangallo KC; Mastovska K; Ngo HL; Reddy CM; Vetter W;
Address:		"Eastern Regional Research Center, Agricultural Research Service, U.S. Department of Agriculture, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA. ehoh@mail.sdsu.edu"
Journal Title:		J Agric Food Chem
Year:		2009
Volume:		57
Issue:		7
Page Number:		2653 - 2660
DOI:		10.1021/jf900462p
ISSN/ISBN:		1520-5118 (Electronic) 0021-8561 (Linking)
Abstract:		"We successfully optimized an analytical method using gel permeation chromatography followed by direct sample introduction comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry to quantify multiple groups of targeted persistent organic pollutants and halogenated natural products (HNPs) simultaneously in fish oil samples. This new method has a wider analytical scope than the traditional approach to use multiple methods to cover each class of compounds. Our analysis revealed that the relatively more volatile and lighter organic compounds, such as polychlorinated biphenyls (PCBs), organochlorine pesticides, and other smaller organohalogen compounds, were still present in two brands of 'PCB-free' cod liver oils, albeit at much lower levels than in an untreated commercial sample. Moreover, the less volatile organic compounds, such as polybrominated diphenyl ethers and brominated HNPs, were detected at similar levels in all three cod liver oils. This suggests that the commercial molecular distillation treatment used for removal of organic/inorganic toxic contaminants is only effective for the lighter organic contaminants"
Keywords:		"Benzofurans/analysis Diet Fish Oils/*chemistry Food Contamination/*analysis Gas Chromatography-Mass Spectrometry/instrumentation/*methods Halogenated Diphenyl Ethers/analysis Humans Hydrocarbons, Chlorinated/analysis Hydrocarbons, Halogenated/*analysis Po;"
Notes:		"MedlineHoh, Eunha Lehotay, Steven J Pangallo, Kristin C Mastovska, Katerina Ngo, Helen L Reddy, Christopher M Vetter, Walter eng 2009/03/07 J Agric Food Chem. 2009 Apr 8; 57(7):2653-60. doi: 10.1021/jf900462p"