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Nat Prod Res

Title:		Phytochemical profile and biological activities of Deverra tortuosa (Desf.)DC.: a desert aromatic shrub widespread in Northern Region of Saudi Arabia
Author(s):		Guetat A; Boulila A; Boussaid M;
Address:		"a Department of Biological Sciences, College of Sciences , Northern Border University , Arar , Saudi Arabia. b Laboratory of Plant Biotechnology, Department of Biology, National Institute of Applied Science and Technology , University of Carthage , Tunis , Tunisia. c Laboratory of Natural Substances LR10INRAP02, National Institute of Research and Physico-Chemical Analyses , Biotechpole of Sidi Thabet , Ariana , Tunisia"
Journal Title:		Nat Prod Res
Year:		2019
Volume:		20180416
Issue:		18
Page Number:		2708 - 2713
DOI:		10.1080/14786419.2018.1460842
ISSN/ISBN:		1478-6427 (Electronic) 1478-6419 (Linking)
Abstract:		"The present study describes the chemical composition of the essential oil of different plant parts of Devrra tortuosa; in vivo and in vitro biological activities of plant extract and essential oils. Apiol was found to be the major component of the oil (between 65.73% and 74.41%). The best antioxidant activities were observed for the oil of flowers (IC50 = 175 mug/ml). The samples of stems and roots exhibit lower antioxidant activity (IC50 = 201 mug/ml and 182 mug/ml, respectively). The values of IC50 showed that the extracts of methanol exhibit the highest antioxidants activities (IC50 = 64.8 102 mug/ml). EOs showed excellent antifungal activity against yeasts with low azole susceptibilities (i.e. Malassezia spp. and Candida krusei). The MIC values of oils varied between 2.85 mg/mL and 27 mg/mL. The obtained results also showed that the plant extracts inhibited the germination and the shoot and root growth of Triticum aestivum seedlings"
Keywords:		"Antifungal Agents/chemistry/pharmacology Antioxidants/chemistry/*pharmacology Apiaceae/*chemistry Candida/drug effects Drug Evaluation, Preclinical/methods Flowers/chemistry Germination/drug effects Microbial Sensitivity Tests Oils, Volatile/*chemistry/*p;"
Notes:		"MedlineGuetat, Arbi Boulila, Abdennacer Boussaid, Mohamed eng Video-Audio Media England 2018/04/17 Nat Prod Res. 2019 Sep; 33(18):2708-2713. doi: 10.1080/14786419.2018.1460842. Epub 2018 Apr 16"