Title: | "Sex-specific aging in flies, worms, and missing great-granddads" |
Address: | "Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: cefinch@usc.edu. Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: jtower@usc.edu" |
DOI: | 10.1016/j.cell.2014.01.028 |
ISSN/ISBN: | 1097-4172 (Electronic) 0092-8674 (Print) 0092-8674 (Linking) |
Abstract: | Two recent studies identify how sex-specific pheromonal factors in flies and worms alter lifespan through metabolic pathways that are shared with mammals. Sex differences in human lifespans imply nonautonomous effects modulated by sex-specific gene-environment interactions that could still include pheromonal mechanisms |
Keywords: | "*Aging Animals Female Gene-Environment Interaction Humans *Life Expectancy Male *Models, Animal Sex Characteristics;" |
Notes: | "MedlineFinch, Caleb E Tower, John eng R21 AG040753/AG/NIA NIH HHS/ AG040753/AG/NIA NIH HHS/ P01 AG026572/AG/NIA NIH HHS/ R01 AG011833/AG/NIA NIH HHS/ AG026572/AG/NIA NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't 2014/02/04 Cell. 2014 Jan 30; 156(3):398-9. doi: 10.1016/j.cell.2014.01.028" |