| Title: | Qualitative analyses of less-volatile organic molecules from female skin scents by comprehensive two dimensional gas chromatography-time of flight mass spectrometry |
| Author(s): | Dolezal P; Kyjakova P; Valterova I; Urban S; |
| Address: | "Department of Analytical Chemistry, University of Chemistry and Technology Prague, Technicka 5, 166 28 Prague 6, Czech Republic. Electronic address: dolezald@vscht.cz. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo n. 2, 166 10 Prague 6, Czech Republic. Department of Analytical Chemistry, University of Chemistry and Technology Prague, Technicka 5, 166 28 Prague 6, Czech Republic" |
| DOI: | 10.1016/j.chroma.2017.04.062 |
| ISSN/ISBN: | 1873-3778 (Electronic) 0021-9673 (Linking) |
| Abstract: | "Instrumental human scent analysis is undoubtedly desirable for many forensic as well medical applications. Most of the previous human scent studies were focused on volatile organic compounds (VOCs) which were analysed by head space solid phase micro-extraction gas chromatography/mass spectrometry (HS-SPME-GC/MS). This method is, however, significantly less sensitive to 'heavier' less volatile compounds emitted from the human skin. These less volatile organic scent molecules probably create the basis of the individual human scent signature, and therefore, our attention is focused mainly on these 'heavier' compounds. The human scent was adsorbed onto purified glass beads and samples were prepared as hexane solutions obtained by extraction from the sampled glass beads. To resolve a lot of very similar molecules, the comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometer (GCxGC-TOFMS) was used to analyse the hexane scent solutions. Using this technique, more than 137 less volatile molecules including organic fatty acids, ketones, aldehydes, simple esters, alcohols, and especially various fatty acid esters with different carbon chains were identified. A considerable number of these molecules were identified in the scent samples for the first time" |
| Keywords: | Adsorption Female Gas Chromatography-Mass Spectrometry/instrumentation/*methods Humans Skin Cream/*chemistry Solid Phase Microextraction/methods Volatile Organic Compounds/*chemistry/isolation & purification Forensic chemistry GCxGC-TOFMS Human scent anal; |
| Notes: | "MedlineDolezal, Petr Kyjakova, Pavlina Valterova, Irena Urban, Stepan eng Evaluation Study Netherlands 2017/05/26 J Chromatogr A. 2017 Jul 7; 1505:77-86. doi: 10.1016/j.chroma.2017.04.062. Epub 2017 May 1" |
