« Previous AbstractDecoding chemical communication in nematodes    Next AbstractThe identification of potential aeroallergen/irritant(s) from oilseed rape (Brassica napus spp. oleifera): volatile organic compounds emitted during flowering progression »

Curr Opin Chem Biol

Title:		Natural products as chemical tools to dissect complex biology in C. elegans
Author(s):		Butcher RA;
Address:		"Department of Chemistry, University of Florida, Gainesville, FL 32611, United States. Electronic address: butcher@chem.ufl.edu"
Journal Title:		Curr Opin Chem Biol
Year:		2019
Volume:		20190515
Issue:
Page Number:		138 - 144
DOI:		10.1016/j.cbpa.2019.03.005
ISSN/ISBN:		1879-0402 (Electronic) 1367-5931 (Print) 1367-5931 (Linking)
Abstract:		"The search for novel pheromones, hormones, and other types of natural products in the nematode Caenorhabditis elegans has accelerated over the last 10-15 years. Many of these natural products perturb fundamental processes such as developmental progression, metabolism, reproductive and somatic aging, and various behaviors and have thus become essential tools for probing these processes, which are difficult to study in higher organisms. Furthermore, given the similarity between C. elegans and parasitic nematodes, these natural products could potentially be used to manipulate the development and behavior of parasitic nematodes and target the infections caused by them"
Keywords:		Animals Biological Products/*metabolism Caenorhabditis elegans/*metabolism;
Notes:		"MedlineButcher, Rebecca A eng R01 GM118775/GM/NIGMS NIH HHS/ Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Review England 2019/05/19 Curr Opin Chem Biol. 2019 Jun; 50:138-144. doi: 10.1016/j.cbpa.2019.03.005. Epub 2019 May 15"