« Previous AbstractFunctional Analysis of the Chemosensory Protein MsepCSP8 From the Oriental Armyworm Mythimna separata    Next Abstract"Comparative analysis of steam distilled floral oils of cacao cultivars (Theobroma cacao L., Sterculiaceae) and attraction of flying insects: Implications for aTheobroma pollination syndrome" »

J Breath Res

Title:		"Effect of a single brushing with two Zn-containing toothpastes on VSC in morning breath: a 12 h, randomized, double-blind, cross-over clinical study"
Author(s):		Young A; Jonski G;
Address:		"Department of Cariology and Gerodontology, Faculty of Dentistry, University of Oslo, PO Box 1109 Blindern, NO-0317 Oslo, Norway. a.y.vik@odont.uio.no"
Journal Title:		J Breath Res
Year:		2011
Volume:		20111201
Issue:		4
Page Number:		46012 -
DOI:		10.1088/1752-7155/5/4/046012
ISSN/ISBN:		1752-7163 (Electronic) 1752-7155 (Linking)
Abstract:		"This randomized, double-blind, 12 h clinical study tested the effect of a single brushing with two Zn-containing toothpastes on volatile sulfur compound (VSC) levels in morning breath. The following toothpastes were each tested by all 28 participants: A-Zn toothpaste, B--experimental toothpaste (Zn citrate + PVM/MA copolymer) and C--control toothpaste without Zn. The evening prior to test days participants brushed their teeth for 2 min with 1 g toothpaste. 12 h later and prior to eating or performing oral hygiene, morning breath levels of VSC (H(2)S, CH(3)SH) were analysed by gas chromatography. Subjects then rinsed for 30 s with 5 ml cysteine and breath samples were analysed for H(2)S (H(2)S(cys)). Median VSC (area under the curve) values were compared for A, B and C and the effects of A and B on VSC were compared with C. Toothpaste B was more effective than both toothpastes A and C in reducing H(2)S, CH(3)SH and H(2)S(cys) (p < 0.05). Compared with toothpaste C, toothpastes A and B reduced H(2)S by 35% and 68%, respectively (p = 0.003), and CH(3)SH by 12% and 47%, respectively (p = 0.002). Toothpaste B reduced H(2)S(cys) by 48% compared with toothpaste C (p = 0.001). It is suggested that the superior effect of the experimental toothpaste was most likely due to a higher Zn concentration combined with longer retention of Zn due to the PVM/MA copolymer"
Keywords:		Adult Breath Tests/*methods Cross-Over Studies Double-Blind Method Female Follow-Up Studies Halitosis/*diagnosis/metabolism/prevention & control Humans Male Oral Hygiene *Toothbrushing Toothpastes/*chemistry Volatile Organic Compounds/*analysis Young Adul;
Notes:		"MedlineYoung, A Jonski, G eng Comparative Study Randomized Controlled Trial Research Support, Non-U.S. Gov't England 2011/12/03 J Breath Res. 2011 Dec; 5(4):046012. doi: 10.1088/1752-7155/5/4/046012. Epub 2011 Dec 1"