| Title: | Mating behavior induces differential Arc expression in the main and accessory olfactory bulbs of adult rats |
| Author(s): | Matsuoka M; Yoshida-Matsuoka J; Sugiura H; Yamagata K; Ichikawa M; Norita M; |
| Address: | "Division of Neurobiology and Anatomy, Niigata University Graduate School of Medical and Dental Sciences, Niigata, 951-8510, Niigata, Japan" |
| DOI: | 10.1016/s0304-3940(02)01187-4 |
| ISSN/ISBN: | 0304-3940 (Print) 0304-3940 (Linking) |
| Abstract: | "The expression of activity-related cytoskeleton-associated protein, Arc, could be useful as a marker for neuronal activity. We investigated Arc-immunoreactivity in both the accessory olfactory bulb (AOB) and the main olfactory bulb (MOB) of adult male rats in response to mating or exposure to female pheromones. Mating behavior strongly enhanced the Arc-immunoreactivity in the granule cell layer of the AOB. However, the enhancement of Arc-immunoreactivity by mating behavior was not observed in the MOB. These results showed that Arc-immunoreactivity was enhanced when the AOB received both afferent and efferent information during mating behavior. Hence, the expression of Arc in the AOB directly associates the pheromonal information with mating behavior. The AOB will provide a useful model to investigate the function of Arc protein" |
| Keywords: | Analysis of Variance Animals Apoptosis Regulatory Proteins Female Immediate-Early Proteins/biosynthesis Immunoblotting Immunohistochemistry Male Muscle Proteins/*biosynthesis/metabolism Olfactory Bulb/cytology/*metabolism Olfactory Pathways/cytology/metab; |
| Notes: | "MedlineMatsuoka, Masato Yoshida-Matsuoka, Junko Sugiura, Hiroko Yamagata, Kanato Ichikawa, Masumi Norita, Masao eng Comparative Study Research Support, Non-U.S. Gov't Ireland 2002/12/03 Neurosci Lett. 2002 Dec 25; 335(2):111-4. doi: 10.1016/s0304-3940(02)01187-4" |
