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Nat Prod Commun

Title:		Identification of safranal as the main allelochemical from saffron (Crocus sativus)
Author(s):		Mardani H; Sekine T; Azizi M; Mishyna M; Fujii Y;
Address:
Journal Title:		Nat Prod Commun
Year:		2015
Volume:		10
Issue:		5
Page Number:		775 - 777
DOI:
ISSN/ISBN:		1934-578X (Print) 1555-9475 (Linking)
Abstract:		"Dried parts of 75 medicinal plant species collected from different regions in Iran were assayed by the Dish Pack Method for volatile allelopathic activity, using Lactuca sativa (lettuce) as the test plant. The highest (60%) inhibition was observed for saffron (stigma of Crocus sativus), followed by Dracocephalum kotschyi, Solanum nigrum and Artemisia aucheri. Safranal was identified as the main chemical by Headspace Gas Chromatography-Mass Spectrometry (HS- GC-MS) analyses of saffron. Moreover, the EC50 of safranal was evaluated as 1.2 mug/L (ppb). This is the first report on allelopathic activity of safranal as a bioactive compound identified from saffron"
Keywords:		Crocus/*chemistry Cyclohexenes/analysis/isolation & purification/*pharmacology Flowers/chemistry Lettuce/drug effects/growth & development Pheromones/analysis/isolation & purification/*pharmacology Plant Extracts/analysis/isolation & purification/*pharmac;
Notes:		"MedlineMardani, Hossein Sekine, Takayuki Azizi, Majid Mishyna, Maryia Fujii, Yoshiharu eng Research Support, Non-U.S. Gov't 2015/06/11 Nat Prod Commun. 2015 May; 10(5):775-7"