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Nat Prod Rep

Title:		"Non-volatile natural products in plant glandular trichomes: chemistry, biological activities and biosynthesis"
Author(s):		Liu Y; Jing SX; Luo SH; Li SH;
Address:		"State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China. shli@mail.kib.ac.cn"
Journal Title:		Nat Prod Rep
Year:		2019
Volume:		36
Issue:		4
Page Number:		626 - 665
DOI:		10.1039/c8np00077h
ISSN/ISBN:		1460-4752 (Electronic) 0265-0568 (Linking)
Abstract:		"Covering: 1960s to end of August 2018 Plant glandular trichomes (GTs) are adaptive structures that are well known as 'phytochemical factories' due to their impressive capacity to biosynthesize and store large quantities of specialized natural products. The natural products in GTs are chemically diverse and mostly function as defense chemicals, therefore GTs are frequently regarded as 'the first defense line' of plants against biotic and abiotic stresses. More importantly, many GT natural products are commercially desirable, thanks to their significant biological activities, thus attracting extensive interest in their biosynthesis. Consequently, it is well known that plant GTs are not only important reservoirs of biologically active natural products but are also a valuable bank of novel biosynthetic genes and enzymes. The non-volatile or oxygenated natural products in plant GTs, which need longer biosynthetic pathways and more energy from the plants, are of particular interest due to their more extensive biological activities and high commercial value. This review mainly focuses on these non-volatile natural products in plant GTs, including their chemistry, biological activities and biosynthesis. The methods employed for investigating natural products and their biosynthesis in plant GTs are also comprehensively discussed"
Keywords:		"Anti-Inflammatory Agents, Non-Steroidal/chemistry/metabolism/pharmacology Antineoplastic Agents, Phytogenic/biosynthesis/chemistry/pharmacology Biological Products/*chemistry/*metabolism/pharmacology Biosynthetic Pathways Flavonoids/biosynthesis/chemistry;"
Notes:		"MedlineLiu, Yan Jing, Shu-Xi Luo, Shi-Hong Li, Sheng-Hong eng Research Support, Non-U.S. Gov't Review England 2018/11/24 Nat Prod Rep. 2019 Apr 17; 36(4):626-665. doi: 10.1039/c8np00077h"