| Title: | "Assessment of liver and renal function tests among gasoline exposed gas station workers in Mekelle city, Tigray region, Northern Ethiopia" |
| Author(s): | Asefaw T; Wolde M; Edao A; Tsegaye A; Teklu G; Tesfay F; Gebremariam G; |
| Address: | "Department of Medical Laboratory Science, College of Health Sciences, Mekelle University, Mekelle, Ethiopia. Department of Medical Laboratory Sciences, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia" |
| DOI: | 10.1371/journal.pone.0239716 |
| ISSN/ISBN: | 1932-6203 (Electronic) 1932-6203 (Linking) |
| Abstract: | "BACKGROUND: Volatile organic compounds such as gasoline and other fuels are associated with a wide variety of deleterious health effects including liver and kidney diseases. Gasoline station workers are exposed to a mixture of hydrocarbons during dispensing. However, no published studies investigated the liver and renal function tests of gasoline station workers in Ethiopia. Therefore the aim of this study was to assess liver and renal function tests among gasoline station workers. METHOD: A comparative cross sectional study was conduct from January 2018 to April 2018 at Mekelle city, Tigray region, Northern Ethiopia. Liver and renal function tests were analyzed on gasoline exposed (n = 43) and controls (n = 47) by Pentra C400 automated clinical chemistry analyzer. Student independent t-test and one way-ANOVA statistical methods were employed using SPSS Ver23. P-value < 0.05 was regarded as statistically significant. RESULT: The mean level of ALT, AST, Urea, creatinine, and uric acid was significantly higher among gasoline stations workers when compared to control study participants. There was also a significant increase in ALT, AST, Urea, creatinine and uric acid among gasoline stations with above 6 years exposure when compared with those exposed for |
| Keywords: | Adult Benzene/adverse effects/analysis Cross-Sectional Studies Ethiopia/epidemiology Female Gasoline/adverse effects/*analysis Humans Kidney/chemistry/*pathology Liver/chemistry/*pathology Male Middle Aged Occupational Diseases Occupational Exposure/analy; |
| Notes: | "MedlineAsefaw, Tsegay Wolde, Mistre Edao, Abebe Tsegaye, Aster Teklu, Gebre Tesfay, Feven Gebremariam, Gebreslassie eng 2020/10/10 PLoS One. 2020 Oct 9; 15(10):e0239716. doi: 10.1371/journal.pone.0239716. eCollection 2020" |
