| Title: | DNAs of the two mating-type alleles of Neurospora crassa are highly dissimilar |
| Author(s): | Glass NL; Vollmer SJ; Staben C; Grotelueschen J; Metzenberg RL; Yanofsky C; |
| Address: | "Department of Physiological Chemistry, University of Wisconsin, Madison 53706" |
| ISSN/ISBN: | 0036-8075 (Print) 0036-8075 (Linking) |
| Abstract: | "The mating-type alleles A and a of Neurospora crassa control mating in the sexual cycle and function in establishing heterokaryon incompatibility in the vegetative cycle. The A and a alleles were cloned, and they were shown to encode both the sexual functions and vegetative incompatibility. The mating-type clones contain nonhomologous DNA segments that are flanked by common DNA sequences. Neurospora crassa and all heterothallic and pseudohomothallic Neurospora species contain a single copy of one mating-type sequence or the other within each haploid genome. The six known self-fertile homothallic isolates contain an A homolog, but only one species also contains a homologous sequences. Homothallism in these species is not due to mating-type switching, as it is in Saccharomyces cerevisiae" |
| Keywords: | "Chromosome Mapping DNA Restriction Enzymes/genetics *DNA, Fungal *Genes, Fungal *Genes, Mating Type, Fungal Mating Factor Neurospora/*genetics Neurospora crassa/*genetics Peptides/*genetics;" |
| Notes: | "MedlineGlass, N L Vollmer, S J Staben, C Grotelueschen, J Metzenberg, R L Yanofsky, C eng GM-08995/GM/NIGMS NIH HHS/ Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. 1988/07/29 Science. 1988 Jul 29; 241(4865):570-3. doi: 10.1126/science.2840740" |
