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Curr Cancer Drug Targets

Title:		Anticancer Properties of Essential Oils: An Overview
Author(s):		Andrade MA; Braga MA; Cesar PHS; Trento MVC; Esposito MA; Silva LF; Marcussi S;
Address:		"Cell Biology Department, Universidade de Brasilia, Distrito Federal, Brazil. Biochemistry Laboratory, Chemistry Department, Universidade Federal de Lavras, Lavras, Minas Gerais, Brazil. Organic Chemistry Laboratory, Chemistry Department, Universidade Federal de Lavras, Lavras, Minas Gerais, Brazil"
Journal Title:		Curr Cancer Drug Targets
Year:		2018
Volume:		18
Issue:		10
Page Number:		957 - 966
DOI:		10.2174/1568009618666180102105843
ISSN/ISBN:		1873-5576 (Electronic) 1568-0096 (Linking)
Abstract:		"BACKGROUND: Essential oils are complex mixtures of low molecular weight compounds extracted from plants. Their main constituents are terpenes and phenylpropanoids, which are responsible for their biological and pharmaceutical properties, such as insecticidal, parasiticidal, antimicrobial, antioxidant, anti-inflammatory, analgesic, antinociceptive, anticarcinogenic, and antitumor properties. Cancer is a complex genetic disease considered as a serious public health problem worldwide, accounting for more than 8 million deaths annually. OBJECTIVE: The activities of prevention and treatment of different types of cancer and the medicinal potential of essential oils are addressed in this review. CONCLUSION: Several studies have demonstrated anti-carcinogenic and antitumor activity for many essential oils obtained from various plant species. They may be used as a substitution to or in addition to conventional anti-cancer therapy. Although many studies report possible mechanisms of action for essential oils compounds, more studies are necessary in order to apply them safely and appropriately in cancer therapy"
Keywords:		"Analgesics/therapeutic use Anti-Inflammatory Agents/therapeutic use Antineoplastic Agents/*therapeutic use Antioxidants/therapeutic use Drug Resistance, Neoplasm Humans Neoplasms/*drug therapy/*prevention & control Oils, Volatile/*therapeutic use Plant Oi;"
Notes:		"MedlineAndrade, Milene Aparecida Braga, Mariana Aparecida Cesar, Pedro Henrique Souza Trento, Marcus Vinicius Cardoso Esposito, Mariana Araujo Silva, Lucilene Fernandes Marcussi, Silvana eng Research Support, Non-U.S. Gov't Review Netherlands 2018/01/04 Curr Cancer Drug Targets. 2018; 18(10):957-966. doi: 10.2174/1568009618666180102105843"