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Annu Rev Microbiol

Title:		Cell-cell communication in gram-positive bacteria
Author(s):		Dunny GM; Leonard BA;
Address:		"Department of Microbiology, University of Minnesota Medical School, Minneapolis 55455, USA. gary-d@biosci.cbs.umn.edu"
Journal Title:		Annu Rev Microbiol
Year:		1997
Volume:		51
Issue:
Page Number:		527 - 564
DOI:		10.1146/annurev.micro.51.1.527
ISSN/ISBN:		0066-4227 (Print) 0066-4227 (Linking)
Abstract:		"In gram-positive bacteria, many important processes are controlled by cell-to-cell communication, which is mediated by extracellular signal molecules produced by the bacteria. Most of these signaling molecules are peptides or modified peptides. Signal processing, in most cases, involves either transduction across the cytoplasmic membrane or import of the signal and subsequent interaction with intracellular effectors. Concentrations of signal in the nanomolar range or below are frequently sufficient for biological activity. The microbial processes controlled by extracellular signaling include the expression of virulence factors, the expression of gene transfer functions, and the production of antibiotics"
Keywords:		4-Butyrolactone/metabolism Anti-Bacterial Agents/metabolism Bacillus subtilis/genetics/metabolism Bacterial Proteins/metabolism Bacteriocins/metabolism Cell Membrane/metabolism Enterococcus faecalis/genetics/metabolism/pathogenicity Gene Expression Regula;
Notes:		"MedlineDunny, G M Leonard, B A eng AI08742/AI/NIAID NIH HHS/ GM49530/GM/NIGMS NIH HHS/ HL51987/HL/NHLBI NIH HHS/ Research Support, U.S. Gov't, P.H.S. Review 1997/01/01 Annu Rev Microbiol. 1997; 51:527-64. doi: 10.1146/annurev.micro.51.1.527"