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Chem Soc Rev


Title:Array sensing using optical methods for detection of chemical and biological hazards
Author(s):Diehl KL; Anslyn EV;
Address:"Department of Chemistry and Biochemistry, The University of Texas, Austin, TX 78712, USA. Anslyn@austin.utexas.edu"
Journal Title:Chem Soc Rev
Year:2013
Volume:42
Issue:22
Page Number:8596 - 8611
DOI: 10.1039/c3cs60136f
ISSN/ISBN:1460-4744 (Electronic) 0306-0012 (Linking)
Abstract:"By mimicking the mammalian senses of taste and smell, artificial arrays of cross-reactive receptors have found use in a variety of sensing applications. Pattern recognition algorithms allow these arrays to be used for discriminating analytes and even for predicting the identity of unknown analytes. Furthermore, in selecting a signaling method for these assays, the choice of optical detection is particularly desirable due to its high sensitivity and the associated convenient instrumentation. This tutorial review provides a brief introduction to array sensing using optical detection and chemometrics. While differential sensing approaches have been used for a number of applications, this review focuses on progress towards the detection of chemical and biological hazards"
Keywords:"Algorithms Bacteria/isolation & purification *Biosensing Techniques Chemical Warfare Agents/analysis Hazardous Substances/analysis Industrial Waste/analysis *Microarray Analysis *Optical Imaging Pattern Recognition, Automated Volatile Organic Compounds/an;"
Notes:"MedlineDiehl, Katharine L Anslyn, Eric V eng England 2013/09/04 Chem Soc Rev. 2013 Nov 21; 42(22):8596-611. doi: 10.1039/c3cs60136f"

 
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