Title: | Plugging it in: signaling circuits and the yeast cell cycle |
Address: | "Curt Wittenberg, Department of Molecular Biology, MB-3, The Scripps Research Institute, 10666 N Torrey Pines Road, La Jolla, CA 92037, USA. curtw@scripps.edu" |
DOI: | 10.1016/s0955-0674(96)80069-x |
ISSN/ISBN: | 0955-0674 (Print) 0955-0674 (Linking) |
Abstract: | Signal transduction pathways provide the means to transmit information and elicit specific responses. Modulation of the cell cycle machinery is one such response. Molecular genetic approaches with budding yeast have been instrumental in elucidating the components of these complex signaling pathways and the inter-relationships among these components. Recent progress has revealed pathways that link extracellular signals with the machinery governing both cell cycle progression and morphogenesis. The nature of the interface between nutritional and checkpoint signals with the cell cycle apparatus is just now emerging |
Keywords: | Animals Cell Cycle/*physiology Cyclic AMP/metabolism Fungal Proteins/metabolism Haploidy Humans Pheromones/metabolism Saccharomyces cerevisiae/cytology/*physiology Signal Transduction/*physiology; |
Notes: | "MedlineWittenberg, C Reed, S I eng GM38328/GM/NIGMS NIH HHS/ GM43487/GM/NIGMS NIH HHS/ GM46006/GM/NIGMS NIH HHS/ Research Support, U.S. Gov't, P.H.S. Review England 1996/04/01 Curr Opin Cell Biol. 1996 Apr; 8(2):223-30. doi: 10.1016/s0955-0674(96)80069-x" |