Title: | Pediatric Asthma Attack and Home Paint Exposure |
Author(s): | Saif NT; Janecki JM; Wanner A; Colin AA; Kumar N; |
Address: | "Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, USA. Division of Pulmonary and Sleep Medicine, University of Miami Health System, Miami, FL 33136, USA. Division of Pediatric Pulmonology, Miller School of Medicine, University of Miami Health System, Miami, FL 33136, USA" |
Journal Title: | Int J Environ Res Public Health |
ISSN/ISBN: | 1660-4601 (Electronic) 1661-7827 (Print) 1660-4601 (Linking) |
Abstract: | "Although asthma mortality has been declining for the past several decades, asthma morbidity is on the rise, largely due to deteriorating indoor air quality and comorbidities, such as allergies. Consumer products and building materials including paints emit volatile organic compounds (VOCs), such as propylene glycol (PG), which is shown to dehydrate respiratory tracts and can contributor to airway remodeling. We hypothesize that paint exposure increases the risk of asthma attacks among children because high levels of VOCs persist indoors for many weeks after painting. Children 1-15 years old visiting two of the University of Miami general pediatric clinics were screened for their history of asthma and paint exposure by interviewing their parents and/or guardians accompanying them to the clinic. They were also asked questions about asthma diagnosis, severity of asthma and allergies and their sociodemographics. The risk of asthma attack among asthmatic children was modeled with respect to paint exposure adjusting for potential confounders using multivariate logistic regressions. Of 163 children, 36 (22%) reported physician-diagnosed asthma and of these, 13 (33%) had an asthma attack during the last one year. Paint exposure was marginally significant in the univariate analysis (OR = 4.04; 95% CI = 0.90-18.87; p < 0.1). However, exposed asthmatic children were 10 times more likely to experience an asthma attack than unexposed asthmatic children (OR = 10.49; CI = 1.16-94.85, p < 0.05) when adjusted for other risk factors. Given paint is one of the sources of indoor VOCs, multiple strategies are warranted to manage the health effects of VOC exposure from paint, including the use of zero-VOC water-based paint, exposure avoidance and clinical interventions" |
Keywords: | "Adolescent *Air Pollution, Indoor/adverse effects/analysis *Asthma/chemically induced/epidemiology Child Child, Preschool Humans *Hypersensitivity Infant Paint/adverse effects *Volatile Organic Compounds/analysis/toxicity VOCs allergies home environment p;" |
Notes: | "MedlineSaif, Nadia T Janecki, Julia M Wanner, Adam Colin, Andrew A Kumar, Naresh eng R01 EY026174/EY/NEI NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Switzerland 2021/05/01 Int J Environ Res Public Health. 2021 Apr 13; 18(8):4118. doi: 10.3390/ijerph18084118" |