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Food Res Int

Title:		"Remela de cachorro (Clavija lancifolia Desf.) fruits from South Amazon: Phenolic composition, biological potential, and aroma analysis"
Author(s):		Paz WHP; de Almeida RA; Braga NA; da Silva FMA; Acho LDR; Lima ES; Boleti APA; Dos Santos EL; Angolini CFF; Bataglion GA; Koolen HHF;
Address:		"Metabolomics and Mass Spectrometry Research Group, Amazonas State University - UEA, 690065-130 Manaus, AM, Brazil; Department of Chemistry, Federal University of Amazonas - UFAM, 69080-900 Manaus, AM, Brazil. Department of Chemistry, Federal University of Amazonas - UFAM, 69080-900 Manaus, AM, Brazil. Faculty of Pharmacy, Federal University of Amazonas - UFAM, 69077-000 Manaus, AM, Brazil. School of Biological and Environmental Sciences, Federal University of Grande Dourados - UFGD, 79825-900 Dourados, MS, Brazil. Institute of Chemistry, University of Campinas - UNICAMP, 13083-970 Campinas, SP, Brazil. Metabolomics and Mass Spectrometry Research Group, Amazonas State University - UEA, 690065-130 Manaus, AM, Brazil. Electronic address: hkoolen@uea.edu.br"
Journal Title:		Food Res Int
Year:		2018
Volume:		20180414
Issue:
Page Number:		112 - 119
DOI:		10.1016/j.foodres.2018.04.019
ISSN/ISBN:		1873-7145 (Electronic) 0963-9969 (Linking)
Abstract:		"Remela de cachorro (Clavija lancifolia Desf.) is an Amazonian native fruit consumed specially in the Purus microregion. Because of its rarity, restricted consumption, and the lack of knowledge about its chemical composition, remela de cachorro fruit was studied in relation to its phenolic and aroma constitution. Using liquid chromatography tandem mass spectrometry (LC-MS/MS), 11 compounds (flavonoids and its glucosides along with organic acids) were tentatively identified by fragmentation patterns. A previously validated method was applied to quantify common antioxidant compounds in the raw pulps, for which kaempferol was the main compound. Gas chromatography mass spectrometry (GC-MS) with headspace solid-phase microextraction (HS-SPME) was employed to assess the aroma composition of remela de cachorro fruit. A total of 27 volatile organic compounds (VOCs) were identified for this fruit, for which benzaldehyde and linalool were the main VOCs. Furthermore, biological activities, such as antioxidant capacity (ABTS, DPPH, and ORAC methods), cytotoxicity, and alpha-glucosidase and lipase inhibitions of the hydroalcoholic extract of remela de cachorro fruit were evaluated. In vitro biological assays revealed the potential of this fruit as a bioactive food that should be further studied and explored in Amazonian products"
Keywords:		"*Antioxidants/analysis/pharmacology Brazil Cell Line, Tumor Cell Survival/drug effects Chlorogenic Acid/analysis/pharmacology Flavonoids/analysis/pharmacology Fruit/*chemistry Glucosides/analysis/pharmacology Humans Odorants/*analysis *Phenols/analysis/ph;"
Notes:		"MedlinePaz, Weider H P de Almeida, Richardson A Braga, Neila A da Silva, Felipe M A Acho, Leonard D R Lima, Emerson S Boleti, Ana Paula A Dos Santos, Edson L Angolini, Celio F F Bataglion, Giovana A Koolen, Hector H F eng Research Support, Non-U.S. Gov't Canada 2018/05/29 Food Res Int. 2018 Jul; 109:112-119. doi: 10.1016/j.foodres.2018.04.019. Epub 2018 Apr 14"