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J Nutr Sci

Title:		Effects of dietary nutrients on volatile breath metabolites
Author(s):		Ajibola OA; Smith D; Spanel P; Ferns GA;
Address:		"Guy Hilton Research Centre, Institute for Science and Technology in Medicine, University of Keele , Thornburrow Drive, Hartshill, Stoke-on-Trent ST4 7QB , UK. Guy Hilton Research Centre, Institute for Science and Technology in Medicine, University of Keele , Thornburrow Drive, Hartshill, Stoke-on-Trent ST4 7QB , UK ; J. Heyrovsky Institute of Physical Chemistry, Academy of Sciences of the Czech Republic , Dolejskova 3, 182 23, Prague 8 , Czech Republic. Division of Medical Education, Brighton and Sussex Medical School, Mayfield House , University of Brighton , Brighton BN1 9PH , UK"
Journal Title:		J Nutr Sci
Year:		2013
Volume:		20131031
Issue:
Page Number:		e34 -
DOI:		10.1017/jns.2013.26
ISSN/ISBN:		2048-6790 (Print) 2048-6790 (Electronic) 2048-6790 (Linking)
Abstract:		"Breath analysis is becoming increasingly established as a means of assessing metabolic, biochemical and physiological function in health and disease. The methods available for these analyses exploit a variety of complex physicochemical principles, but are becoming more easily utilised in the clinical setting. Whilst some of the factors accounting for the biological variation in breath metabolite concentrations have been clarified, there has been relatively little work on the dietary factors that may influence them. In applying breath analysis to the clinical setting, it will be important to consider how these factors may affect the interpretation of endogenous breath composition. Diet may have complex effects on the generation of breath compounds. These effects may either be due to a direct impact on metabolism, or because they alter the gastrointestinal flora. Bacteria are a major source of compounds in breath, and their generation of H2, hydrogen cyanide, aldehydes and alkanes may be an indicator of the health of their host"
Keywords:		"Breath analysis Gut flora Macronutrients Micronutrients PTR, proton transfer reaction SIFT, selected ion flow tube Selected ion flow tube-MS VOC, volatile organic compounds ppbv, parts per billion by volume;"
Notes:		"PubMed-not-MEDLINEAjibola, Olawunmi A Smith, David Spanel, Patrik Ferns, Gordon A A eng England 2013/01/01 J Nutr Sci. 2013 Oct 31; 2:e34. doi: 10.1017/jns.2013.26. eCollection 2013"