« Previous AbstractVolatile organic compounds as markers of quality changes during the storage of wild rocket    Next AbstractPrimary culture of antennal cells of Mamestra brassicae: morphology of cell types and evidence for biosynthesis of pheromone-binding proteins in vitro »

Antioxidants (Basel)

Title:		"Value-Added Compounds with Antimicrobial, Antioxidant, and Enzyme-Inhibitory Effects from Post-Distillation and Post-Supercritical CO(2) Extraction By-Products of Rosemary"
Author(s):		Luca SV; Zengin G; Sinan KI; Korona-Glowniak I; Minceva M; Skalicka-Wozniak K; Trifan A;
Address:		"Biothermodynamics, TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany. Physiology and Biochemistry Research Laboratory, Department of Biology, Science Faculty, Selcuk University, 42130 Konya, Turkey. Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Medical University of Lublin, 20-093 Lublin, Poland. Department of Natural Products Chemistry, Medical University of Lublin, 20-093 Lublin, Poland. Department of Pharmacognosy and Phytotherapy, Faculty of Pharmacy, 'Grigore T. Popa' University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"
Journal Title:		Antioxidants (Basel)
Year:		2023
Volume:		20230121
Issue:		2
Page Number:		-
DOI:		10.3390/antiox12020244
ISSN/ISBN:		2076-3921 (Print) 2076-3921 (Electronic) 2076-3921 (Linking)
Abstract:		"Hydrodistillation is the main technique to obtain essential oils from rosemary for the aroma industry. However, this technique is wasteful, producing numerous by-products (residual water, spent materials) that are usually discarded in the environment. Supercritical CO(2) (SC-CO(2)) extraction is considered an alternative greener technology for producing aroma compounds. However, there have been no discussions about the spent plant material leftover. Therefore, this work investigated the chemical profile (GC-MS, LC-HRMS/MS) and multi-biological activity (antimicrobial, antioxidant, enzyme inhibitory) of several raw rosemary materials (essential oil, SC-CO(2) extracts, solvent extracts) and by-products/waste materials (post-distillation residual water, spent plant material extracts, and post-supercritical CO(2) spent plant material extracts). More than 55 volatile organic compounds (e.g., pinene, eucalyptol, borneol, camphor, caryophyllene, etc.) were identified in the rosemary essential oil and SC-CO(2) extracts. The LC-HRMS/MS profiling of the solvent extracts revealed around 25 specialized metabolites (e.g., caffeic acid, rosmarinic acid, salvianolic acids, luteolin derivatives, rosmanol derivatives, carnosol derivatives, etc.). Minimum inhibitory concentrations of 15.6-62.5 mg/L were obtained for some rosemary extracts against Micrococcus luteus, Bacilus cereus, or Staphylococcus aureus MRSA. Evaluated in six different in vitro tests, the antioxidant potential revealed strong activity for the polyphenol-containing extracts. In contrast, the terpene-rich extracts were more potent in inhibiting various key enzymes (e.g., acetylcholinesterase, butyrylcholinesterase, tyrosinase, amylase, and glucosidase). The current work brings new insightful contributions to the continuously developing body of knowledge about the valorization of rosemary by-products as a low-cost source of high-added-value constituents in the food, pharmaceutical, and cosmeceutical industries"
Keywords:		Lc-hrms/ms Rosmarinus officinalis Salvia rosmarinus aromatic herbs essential oils residues wastes;
Notes:		"PubMed-not-MEDLINELuca, Simon Vlad Zengin, Gokhan Sinan, Kouadio Ibrahime Korona-Glowniak, Izabela Minceva, Mirjana Skalicka-Wozniak, Krystyna Trifan, Adriana eng DS 28/Medical University of Lublin/ Switzerland 2023/02/26 Antioxidants (Basel). 2023 Jan 21; 12(2):244. doi: 10.3390/antiox12020244"