| Title: | A selective chemiresistive sensor for the cancer-related volatile organic compound hexanal by using molecularly imprinted polymers and multiwalled carbon nanotubes |
| Author(s): | Janfaza S; Banan Nojavani M; Nikkhah M; Alizadeh T; Esfandiar A; Ganjali MR; |
| Address: | "Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Jalal Ale Ahmad Highway, Tehran, 14117, Iran. Department of Biomaterials, Faculty of Interdisciplinary Sciences, Tarbiat Modares University, Jalal Ale Ahmad Highway, Tehran, 14117, Iran. Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Jalal Ale Ahmad Highway, Tehran, 14117, Iran. m_nikkhah@modares.ac.ir. Department of Analytical Chemistry, Faculty of Chemistry, University College of Science, University of Tehran, P.O. Box 14155-6455, Tehran, Iran. Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, Tehran, Iran. Condensed Matter National Laboratory, Institute for Research in Fundamental Sciences, P.O. Box 1956838861, Tehran, Iran" |
| DOI: | 10.1007/s00604-019-3241-z |
| ISSN/ISBN: | 1436-5073 (Electronic) 0026-3672 (Linking) |
| Abstract: | "A chemiresistive sensor is described for the lung cancer biomarker hexanal. A composite consisting of molecularly imprinted polymer nanoparticles and multiwalled carbon nanotubes was used in the sensor that is typically operated at a voltage of 4 V and is capable of selectively sensing gaseous hexanal at room temperature. It works in the 10 to 200 ppm concentration range and has a 10 ppm detection limit (at S/N = 3). The sensor signal recovers to a value close to its starting value without the need for heating even after exposure to relatively high levels of hexanal. Graphical abstract Schematic presentation of a chemiresistive sensor for detection of hexanal, a cancer biomarker. The hexanal-imprinted polymeric nanoparticles were synthesized, mixed with multiwalled carbon nanotubes and coated on the surface of an interdigitated electrode to produce a nanocomposite chemiresistor gas sensor for hexanal" |
| Keywords: | "Aldehydes/*analysis Biomarkers, Tumor/analysis Biosensing Techniques Electrochemical Techniques Electrodes Gases/chemistry Humans Limit of Detection Lung Neoplasms/*diagnosis Methacrylates/chemistry *Molecular Imprinting Nanocomposites/chemistry Nanoparti;" |
| Notes: | "MedlineJanfaza, Sajjad Banan Nojavani, Maryam Nikkhah, Maryam Alizadeh, Taher Esfandiar, Ali Ganjali, Mohammad Reza eng Austria 2019/02/02 Mikrochim Acta. 2019 Feb 1; 186(3):137. doi: 10.1007/s00604-019-3241-z" |
