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Mol Cell Biol

Title:		The Saccharomyces cerevisiae SPT13/GAL11 gene has both positive and negative regulatory roles in transcription
Author(s):		Fassler JS; Winston F;
Address:		"Department of Biology, University of Iowa, Iowa City 52242"
Journal Title:		Mol Cell Biol
Year:		1989
Volume:		9
Issue:		12
Page Number:		5602 - 5609
DOI:		10.1128/mcb.9.12.5602-5609.1989
ISSN/ISBN:		0270-7306 (Print) 1098-5549 (Electronic) 0270-7306 (Linking)
Abstract:		"To understand the function of SPT13, a gene encoding a trans-acting factor involved in regulation of Ty-mediated gene expression, we have cloned and sequenced the gene. Our analysis revealed that SPT13 is the same gene as GAL11, a gene in which mutations cause reduced expression of some GAL4-regulated genes. Further analysis of spt13/gal11 mutants suggested that the SPT13 gene also affects transcription of genes involved in mating-type specialization. We show here that SPT13 has both positive and negative regulatory roles in transcription"
Keywords:		"Blotting, Northern Cloning, Molecular/methods *Gene Expression Regulation, Fungal *Genes, Fungal *Genes, Regulator Genotype Mating Factor Mutation Nucleic Acid Hybridization Peptides/genetics Plasmids RNA, Fungal/genetics/isolation & purification Saccharo;"
Notes:		"MedlineFassler, J S Winston, F eng GM32967/GM/NIGMS NIH HHS/ GM40306/GM/NIGMS NIH HHS/ Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. 1989/12/01 Mol Cell Biol. 1989 Dec; 9(12):5602-9. doi: 10.1128/mcb.9.12.5602-5609.1989"