| Title: | Personal NO(2) and Volatile Organic Compounds Exposure Levels are Associated with Markers of Cardiovascular Risk in Women in the Cape Town Region of South Africa |
| Author(s): | Everson F; De Boever P; Nawrot TS; Goswami N; Mthethwa M; Webster I; Martens DS; Mashele N; Charania S; Kamau F; Strijdom H; |
| Address: | "Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, P.O. Box 241, Cape Town 8000, South Africa. Health Unit, Flemish Institute for Technological Research (VITO), 2400 Mol, Belgium. patrick.deboever@vito.be. Centre for Environmental Sciences, Hasselt University, 3590 Diepenbeek, Belgium. patrick.deboever@vito.be. Centre for Environmental Sciences, Hasselt University, 3590 Diepenbeek, Belgium. Division of Physiology, Otto Loewi Research Center of Vascular Biology, Immunity and Inflammation, Medical University of Graz, 8036 Graz, Austria" |
| Journal Title: | Int J Environ Res Public Health |
| ISSN/ISBN: | 1660-4601 (Electronic) 1661-7827 (Print) 1660-4601 (Linking) |
| Abstract: | "Exposure to ambient NO(2) and benzene, toluene ethyl-benzene and m+p- and o-xylenes (BTEX) is associated with adverse cardiovascular effects, but limited information is available on the effects of personal exposure to these compounds in South African populations. This 6-month follow-up study aims to determine 7-day personal ambient NO(2) and BTEX exposure levels via compact passive diffusion samplers in female participants from Cape Town, and investigate whether exposure levels are associated with cardiovascular risk markers. Overall, the measured air pollutant exposure levels were lower compared to international standards. NO(2) was positively associated with systolic and diastolic blood pressure (SBP and DBP), and inversely associated with the central retinal venular equivalent (CRVE) and mean baseline brachial artery diameter. o-xylene was associated with DBP and benzene was strongly associated with carotid intima media thickness (cIMT). Our findings showed that personal air pollution exposure, even at relatively low levels, was associated with several markers of cardiovascular risk in women residing in the Cape Town region" |
| Keywords: | Adult Air Pollutants/analysis Cardiovascular Diseases/*chemically induced/epidemiology *Environmental Exposure Female Follow-Up Studies Humans Nitrogen Dioxide/*toxicity Risk Factors South Africa/epidemiology Volatile Organic Compounds/analysis/*toxicity; |
| Notes: | "MedlineEverson, Frans De Boever, Patrick Nawrot, Tim S Goswami, Nandu Mthethwa, Mashudu Webster, Ingrid Martens, Dries S Mashele, Nyiko Charania, Sana Kamau, Festus Strijdom, Hans eng Research Support, Non-U.S. Gov't Switzerland 2019/07/03 Int J Environ Res Public Health. 2019 Jun 28; 16(13):2284. doi: 10.3390/ijerph16132284" |
