| Title: | Research challenges in endocrine aspects of canine ovarian cycles |
| Address: | "Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA" |
| ISSN/ISBN: | 1439-0531 (Electronic) 0936-6768 (Linking) |
| Abstract: | Significant deficiencies exist in understanding factors controlling the nature and timing of critical endocrine changes in canine ovarian cycles. The following merit further study: changes in steroid clearance and binding; mathematically modelling periovulatory hormone rate of change interactions; luteal gonadotropin dependence; endogenous circannual cycles underlying the ovarian cycle; importance of periovulatory follicular steroid dynamics on granulosa and oocytes; in vitro capacity of anoestrous ovarian tissue to demonstrate roles of individual gonadotropins and steroid precursors to increase oestradiol production; factors affecting secretion and activation of the canine female sex pheromone |
| Keywords: | Animals Dogs/*physiology Estrous Cycle/*physiology Female Gonadal Steroid Hormones/*blood/*metabolism Ovary/*physiology; |
| Notes: | "MedlineConcannon, P W eng 1-HD-2-2725/HD/NICHD NIH HHS/ RR03226/RR/NCRR NIH HHS/ SO7-RR05462/RR/NCRR NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review Germany 2013/01/04 Reprod Domest Anim. 2012 Dec; 47 Suppl 6:6-12. doi: 10.1111/rda.12121" |
