| Title: | Real-time sample analysis using a sampling probe and miniature mass spectrometer |
| Author(s): | Chen CH; Lin Z; Tian R; Shi R; Cooks RG; Ouyang Z; |
| Address: | "Weldon School of Biomedical Engineering, Purdue University , West Lafayette, Indiana 47907, United States. Department of Basic Medical Sciences, School of Veterinary Medicine, Purdue University , West Lafayette, Indiana 47907, United States. Department of Chemistry, Purdue University , West Lafayette, Indiana 47907, United States" |
| DOI: | 10.1021/acs.analchem.5b01943 |
| ISSN/ISBN: | 1520-6882 (Electronic) 0003-2700 (Print) 0003-2700 (Linking) |
| Abstract: | "A miniature mass spectrometry system with a sampling probe has been developed for real-time analysis of chemicals from sample surfaces. The sampling probe is 1.5 m in length and is comprised of one channel for introducing the spray and the other channel for transferring the charged species back to the Mini MS. This system provides a solution to the problem of real-time mass spectrometry analysis of a three-dimensional object in the field and is successful with compounds including those in inks, agrochemicals, explosives, and animal tissues. This system can be implemented in the form of a backpack MS with a sampling probe for forensic analysis or in the form of a compact MS with an intrasurgical probe for tissue analysis" |
| Keywords: | Animals Brain Escherichia coli/chemistry Ink Intestines/chemistry Lipids/analysis Liver/chemistry Lung/chemistry Mass Spectrometry/*instrumentation Rats Surface Properties Time Factors Volatile Organic Compounds/analysis; |
| Notes: | "MedlineChen, Chien-Hsun Lin, Ziqing Tian, Ran Shi, Riyi Cooks, R Graham Ouyang, Zheng eng R01 GM106016/GM/NIGMS NIH HHS/ 1R01GM106016/GM/NIGMS NIH HHS/ Research Support, N.I.H., Extramural 2015/08/04 Anal Chem. 2015 Sep 1; 87(17):8867-73. doi: 10.1021/acs.analchem.5b01943. Epub 2015 Aug 10" |
