Title: | Mitochondrial DNA diversity and the origin of Chinese indigenous sheep |
Author(s): | Zhao E; Yu Q; Zhang N; Kong D; Zhao Y; |
Address: | "College of Animal Science and Technology, Chongqing Key Laboratory of Forage & Herbivore, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Beibei, Chongqing, 400716, China" |
DOI: | 10.1007/s11250-013-0420-5 |
ISSN/ISBN: | 1573-7438 (Electronic) 0049-4747 (Linking) |
Abstract: | "Large-scale mitochondrial DNA (mtDNA) D-loop sequences data from previous studies were investigated to obtain genetic information which contributes to a better understanding of the genetic diversity and history of modern sheep. In this study, we analyzed mtDNA D-loop sequences of 963 individuals from 16 Chinese indigenous breeds that distributed seven geographic regions. Phylogenetic analysis showed that all three previously defined haplogroups A, B, and C were found in all breeds among different regions except in Southwest China mountainous region, which had only the A and B haplogroups. The weak phylogeographic structure was observed among Chinese indigenous sheep breeds distribution regions and this could be attributable to long-term strong gene flow among regions induced by the human migration, commercial trade, and extensive transport of sheep. The estimation of demographic parameters from mismatch analyses showed that haplogroups A and B had at least one demographic expansion of indigenous sheep in China" |
Keywords: | "Animals China DNA, Mitochondrial/*genetics Evolution, Molecular Genetic Variation Haplotypes Phylogeny Sheep/*classification/*genetics;" |
Notes: | "MedlineZhao, Erhu Yu, Qian Zhang, Nanyang Kong, Deying Zhao, Yongju eng 2013/05/28 Trop Anim Health Prod. 2013 Nov; 45(8):1715-22. doi: 10.1007/s11250-013-0420-5. Epub 2013 May 26" |