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J Chromatogr B Analyt Technol Biomed Life Sci

Title:		Breath analysis: technical developments and challenges in the monitoring of human exposure to volatile organic compounds
Author(s):		Tang Z; Liu Y; Duan Y;
Address:		"Research Center of Analytical Instrumentation, Analytical Testing Center, Sichuan University, Chengdu, China. Research Center of Analytical Instrumentation, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China. Electronic address: yduan@scu.edu.cn"
Journal Title:		J Chromatogr B Analyt Technol Biomed Life Sci
Year:		2015
Volume:		20150904
Issue:
Page Number:		285 - 299
DOI:		10.1016/j.jchromb.2015.08.041
ISSN/ISBN:		1873-376X (Electronic) 1570-0232 (Linking)
Abstract:		"At present, there is a growing concern about human quality of life. In particular, there is an awareness of the impact of volatile organic compounds (VOCs) on the environment and human health, so the monitoring of human exposure to VOCs is an increasingly urgent need. Biomonitoring is theoretically more accurate compared with traditional ambient air monitoring, and it plays an essential role in human environmental exposure assessment. Breath analysis is a biomonitoring method with many advantages, which is applicable to assessments of human exposure to a large number of VOCs. Techniques are being developed to improve the sensitivity and precision of breath analysis based on in-direct and direct measurements which will be reviewed in this paper. This paper briefly reviews the frequently used methods in both of these categories, specifically highlighting some promising new techniques. Furthermore, this review also provides theoretical background knowledge about the use of breath analysis as a biomonitoring tool for human exposure assessment. A review of the application of breath analysis to human exposure monitoring during last two decades is also provided according to occupational/non-occupational exposure. Obstacles and potential challenges in this field are also summarized. Based on the gradual improvements in the theoretical basis and technology reviewed in this paper, breath analysis is an enormous potential approach for the monitoring of human exposure to VOCs"
Keywords:		*Breath Tests *Environmental Exposure Humans Volatile Organic Compounds/*analysis Biomonitoring Breath analysis Environmental exposure Occupational exposure Technology;
Notes:		"MedlineTang, Zhentao Liu, Yong Duan, Yixiang eng Research Support, Non-U.S. Gov't Review Netherlands 2015/09/08 J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1; 1002:285-99. doi: 10.1016/j.jchromb.2015.08.041. Epub 2015 Sep 4"