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Mar Drugs

Title:		Chemical Composition and In Vitro Antioxidant and Antimicrobial Activities of the Marine Cyanolichen Lichina pygmaea Volatile Compounds
Author(s):		Sanad H; Belattmania Z; Nafis A; Hassouani M; Mazoir N; Reani A; Hassani L; Vasconcelos V; Sabour B;
Address:		"Laboratory of Plant Biotechnology, Ecology and Ecosystem Valorization-URL CNRST N degrees 10, Faculty of Sciences El Jadida, University Chouaib Doukkali, P.O. Box 20, El Jadida 24000, Morocco. Department of Biology, Faculty of Sciences El Jadida, University Chouaib Doukkali, P.O. Box 20, El Jadida 24000, Morocco. CIIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixoes, Av. General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal. Laboratory of Microbial Biotechnologies, Agrosciences and Environment, Faculty of Sciences Semlalia, University Cadi Ayyad, P.O. Box 2390, Marrakech 40001, Morocco. Department of Biology, Faculty of Sciences, University of Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal"
Journal Title:		Mar Drugs
Year:		2022
Volume:		20220225
Issue:		3
Page Number:		-
DOI:		10.3390/md20030169
ISSN/ISBN:		1660-3397 (Electronic) 1660-3397 (Linking)
Abstract:		"Volatile compounds from the marine cyanolichen Lichina pygmaea, collected from the Moroccan Atlantic coast, were extracted by hydrodistillation and their putative chemical composition was investigated by gas chromatography coupled to mass spectrometry (GC/MS). Based on the obtained results, Lichina pygmaea volatile compounds (LPVCs) were mainly dominated by sesquiterpenes compounds, where gamma-himachalene, beta-himachalene, (2E,4E)-2,4 decadienal and alpha-himachalene were assumed to be the most abundant constituents, with percentage of 37.51%, 11.71%, 8.59% and 7.62%, respectively. LPVCs depicted significant antimicrobial activity against all tested strains (Staphylococcus aureus CCMM B3, Pseudomonas aeruginosa DSM 50090, Escherichia coli ATCC 8739 and Candida albicans CCMM-L4) with minimum inhibitory concentration (MIC) values within the range of 1.69-13.5 mg/mL. Moreover, this LPVC showed interesting scavenging effects on the 2,2-diphenyl-1-picrylhydrazyl radical with an IC(50) of 0.21 mg/mL. LPVCs could be an approving resource with moderate antimicrobial potential and interesting antioxidant activity for cosmetics and pharmaceutical applications"
Keywords:		*Anti-Infective Agents/chemistry/isolation & purification/pharmacology *Antioxidants/chemistry/isolation & purification/pharmacology Ascomycota/*chemistry Biphenyl Compounds/chemistry Candida albicans/drug effects/growth & development Escherichia coli/dru;
Notes:		"MedlineSanad, Hiba Belattmania, Zahira Nafis, Ahmed Hassouani, Meryem Mazoir, Noureddine Reani, Abdeltif Hassani, Lahcen Vasconcelos, Vitor Sabour, Brahim eng UIDB/04423/2020/Fundacao para a Ciencia e Tecnologia/ Switzerland 2022/03/25 Mar Drugs. 2022 Feb 25; 20(3):169. doi: 10.3390/md20030169"