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Eur J Neurosci

Title:		Changes in electrophysiological activity in the accessory olfactory bulb and medial amygdala associated with mate recognition in mice
Author(s):		Binns KE; Brennan PA;
Address:		"Sub-Department of Animal Behaviour, Department of Zoology, University of Cambridge, High Street, Madingley, Cambridge CB3 8AA, UK"
Journal Title:		Eur J Neurosci
Year:		2005
Volume:		21
Issue:		9
Page Number:		2529 - 2537
DOI:		10.1111/j.1460-9568.2005.04090.x
ISSN/ISBN:		0953-816X (Print) 0953-816X (Linking)
Abstract:		"The ability of female mice to recognize their mate's pheromonal identity is critical for the maintenance of their pregnancy and is hypothesized to involve increases in the inhibitory control of mitral/tufted projection neurons in the accessory olfactory bulb. Local field potential recordings from this region of freely behaving female mice showed oscillating neural activity over a wide range of frequencies, which was affected by chemosensory input and prior experience. Mating caused lasting increases in the baseline neural activity in the accessory olfactory bulb, with large increases in the amplitude of local field potential oscillations across a range of frequencies. Exposure to the mate's urinary cues remained effective in increasing the power of these oscillations following mating, but urinary cues from an unfamiliar male were ineffective. A differential response to the familiar and unfamiliar chemosignals was also observed at the level of the amygdala following mating. Individual neurons in the medial amygdala responded more strongly to urine from an unfamiliar male than from the mating male. These findings are consistent with the selective enhancement of inhibition of the familiar pheromonal signal at the level of the accessory olfactory bulb, which is proposed to underlie recognition of the mating male"
Keywords:		"Amygdala/*physiology Animals Electrodes, Implanted Electrophysiology Female Mice Mice, Inbred BALB C Olfactory Bulb/*physiology Pheromones/*physiology Recognition, Psychology/*physiology Sexual Behavior, Animal/*physiology Social Behavior Stimulation, Che;"
Notes:		"MedlineBinns, K E Brennan, P A eng Research Support, Non-U.S. Gov't France 2005/06/04 Eur J Neurosci. 2005 May; 21(9):2529-37. doi: 10.1111/j.1460-9568.2005.04090.x"