Title: | The impact of indoor air quality on respiratory health of older people living in nursing homes: spirometric and exhaled breath condensate assessments |
Author(s): | Belo J; Carreiro-Martins P; Papoila AL; Palmeiro T; Caires I; Alves M; Nogueira S; Aguiar F; Mendes A; Cano M; Botelho MA; Neuparth N; |
Address: | "H&TRC- Health & Technology Research Center, ESTeSL- Escola Superior de Tecnologia da Saude, Instituto Politecnico de Lisboa , Lisbon , Portugal. Integrated Pathophysiological Mechanisms Research Group, Nova Medical School, CEDOC , Lisbon , Portugal. Servico de Imunoalergologia, Hospital de Dona Estefania, Centro Hospitalar de Lisboa Central, EPE , Lisbon , Portugal. Epidemiology and Statistics Analysis Unit, Research Centre, Centro Hospitalar de Lisboa Central, EPE, CEAUL , Lisbon , Portugal. NOVA Medical School/Faculdade de Ciencias Medicas, Universidade Nova de Lisboa , Lisbon , Portugal. CEDOC, Integrated Pathophysiological Mechanisms Research Group, Nova Medical School , Lisbon , Portugal. DINAMIACET - Centre for Socioeconomic and Territorial Studies, ISCTE, Lisbon University Institute , Lisbon , Portugal. Environmental Health Department, National Institute of Health Doutor Ricardo Jorge , Lisbon , Portugal. Environmental Health Department, National Institute of Health , Porto , Portugal. Institute of Public Health (ISPUP), Porto University , Porto , Portugal" |
Journal Title: | J Environ Sci Health A Tox Hazard Subst Environ Eng |
DOI: | 10.1080/10934529.2019.1637206 |
ISSN/ISBN: | 1532-4117 (Electronic) 1093-4529 (Linking) |
Abstract: | "In the Portuguese Geriatric Study of the Health Effects of Indoor Air Quality in Senior Nursing Homes, we aimed to evaluate the impact of indoor air contaminants on the respiratory symptoms and biomarkers in a sample of elderly living in nursing homes. A total of 269 elderly answered a health questionnaire, performed a spirometry and 150 out of these collected an exhaled breath condensate sample for pH and nitrites analysis. The study included the evaluation of indoor chemical and microbiological contaminants. The median age of the participants was 84 (78-87) years and 70.6% were women. The spirometric data indicated the presence of airway obstruction in 14.5% of the sample. Median concentrations of air pollutants did not exceed the existing standards, although increased peak values were observed. In the multivariable analysis, each increment of 100 microg/m(3) of total volatile organic compounds was associated with the odds of respiratory infection in the previous three months ( OR?T =1.05; 95% CI: 1.00-1.09). PM(2.5) concentrations were inversely associated with pH values ( beta?T = -0.04, 95%: -0.06 to -0.01, for each increment of 10 microg/m(3)). Additionally, a direct and an inverse association were found between total bacteria and FEV(1)/FVC and FVC, respectively" |
Keywords: | "Aged Aged, 80 and over Air Pollutants/*analysis/toxicity Air Pollution, Indoor/adverse effects/analysis *Breath Tests Female Humans Hydrogen-Ion Concentration Male Nitrites/analysis *Nursing Homes Particulate Matter/analysis/toxicity Portugal/epidemiology;" |
Notes: | "MedlineBelo, Joana Carreiro-Martins, Pedro Papoila, Ana L Palmeiro, Teresa Caires, Iolanda Alves, Marta Nogueira, Susana Aguiar, Fatima Mendes, Ana Cano, Manuela Botelho, Maria A Neuparth, Nuno eng England 2019/07/06 J Environ Sci Health A Tox Hazard Subst Environ Eng. 2019; 54(12):1153-1158. doi: 10.1080/10934529.2019.1637206. Epub 2019 Jul 5" |