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Appl Environ Microbiol


Title:Description of a 23.9-kilobase chromosomal deletion containing a region encoding fsr genes which mainly determines the gelatinase-negative phenotype of clinical isolates of Enterococcus faecalis in urine
Author(s):Nakayama J; Kariyama R; Kumon H;
Address:"Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan. nakayama@agr.kyushu-u.ac.jp"
Journal Title:Appl Environ Microbiol
Year:2002
Volume:68
Issue:6
Page Number:3152 - 3155
DOI: 10.1128/AEM.68.6.3152-3155.2002
ISSN/ISBN:0099-2240 (Print) 1098-5336 (Electronic) 0099-2240 (Linking)
Abstract:"Expression of virulence-related extracellular proteases, gelatinase, and serine protease of Enterococcus faecalis is regulated by a quorum-sensing system encoded by the fsr gene cluster. In this study, a 23.9-kb chromosomal deletion containing the fsr gene cluster region was found to be present in the majority (79%) of gelatinase-negative clinical isolates of E. faecalis from urine"
Keywords:"Bacterial Proteins/genetics/*metabolism *Chromosome Deletion Chromosomes, Bacterial Endopeptidases/genetics Enterococcus faecalis/*genetics/metabolism Gelatinases/deficiency/*metabolism Humans Lactones Molecular Weight Multigene Family Peptides, Cyclic Ph;"
Notes:"MedlineNakayama, Jiro Kariyama, Reiko Kumon, Hiromi eng 2002/06/01 Appl Environ Microbiol. 2002 Jun; 68(6):3152-5. doi: 10.1128/AEM.68.6.3152-3155.2002"

 
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