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Toxicol Lett


Title:Household exposure models
Author(s):McKone TE;
Address:"Environmental Sciences Division, Lawrence Livermore National Laboratory, Livermore, CA 94550"
Journal Title:Toxicol Lett
Year:1989
Volume:49
Issue:2-Mar
Page Number:321 - 339
DOI: 10.1016/0378-4274(89)90040-4
ISSN/ISBN:0378-4274 (Print) 0378-4274 (Linking)
Abstract:"Human exposure to volatile organic compounds (VOCs) in tap water is often assumed to be dominated by ingestion of drinking water. This paper addresses the relative importance of inhalation and dermal exposure in a typical household. A three-compartment model is used to simulate the 24-h concentration history of VOCs in the shower, bathroom, and remaining household volumes as a result of tap water use. Mass transfers from water to air are derived from measured data for radon and used to estimate mass-transfer properties for VOCs. The model is used to calculate a range of concentrations and human exposures in U.S. dwellings. The estimated ratio of household-inhalation uptake to ingestion uptake is in the range of 1-6 for VOCs. A dermal absorption model is used to assess exposure across the skin boundary during baths and showers. The ratio of dermal exposure to ingestion exposure is in the range 0.6-1"
Keywords:"*Environmental Exposure Humans Models, Theoretical Water Pollutants/*toxicity Water Pollutants, Chemical/*toxicity *Water Supply;"
Notes:"MedlineMcKone, T E eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review Netherlands 1989/12/01 Toxicol Lett. 1989 Dec; 49(2-3):321-39. doi: 10.1016/0378-4274(89)90040-4"

 
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