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Science


Title:Bile Acid secreted by male sea lamprey that acts as a sex pheromone
Author(s):Li W; Scott AP; Siefkes MJ; Yan H; Liu Q; Yun SS; Gage DA;
Address:"Department of Fisheries and Wildlife, Michigan State University, East Lansing, MI 48824, USA. Liweim@msu.edu"
Journal Title:Science
Year:2002
Volume:296
Issue:5565
Page Number:138 - 141
DOI: 10.1126/science.1067797
ISSN/ISBN:1095-9203 (Electronic) 0036-8075 (Linking)
Abstract:"We show that reproductively mature male sea lampreys release a bile acid that acts as a potent sex pheromone, inducing preference and searching behavior in ovulated female lampreys. The secreted bile acid 7alpha,12alpha,24-trihydroxy-5alpha-cholan-3-one 24-sulfate was released in much higher amounts relative to known vertebrate steroid pheromones and may be secreted through the gills. Hence, the male of this fish species signals both its reproductive status and location to females by secreting a pheromone that can act over long distances"
Keywords:"Animals Bile Acids and Salts/chemistry/isolation & purification/metabolism/*physiology Cholic Acids/chemistry/isolation & purification/*physiology Chromatography, High Pressure Liquid Chromatography, Thin Layer Female Gills/cytology/metabolism Lampreys/*p;"
Notes:"MedlineLi, Weiming Scott, Alexander P Siefkes, Michael J Yan, Honggao Liu, Qin Yun, Sang-Seon Gage, Douglas A eng Research Support, Non-U.S. Gov't 2002/04/06 Science. 2002 Apr 5; 296(5565):138-41. doi: 10.1126/science.1067797"

 
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