| Title: | "Amino acid sequence of pheromone-biosynthesis-activating neuropeptide (PBAN) of the silkworm, Bombyx mori" |
| Author(s): | Kitamura A; Nagasawa H; Kataoka H; Inoue T; Matsumoto S; Ando T; Suzuki A; |
| Address: | "Department of Agricultural Chemistry, Faculty of Agriculture, University of Tokyo, Japan" |
| Journal Title: | Biochem Biophys Res Commun |
| DOI: | 10.1016/0006-291x(89)92168-2 |
| ISSN/ISBN: | 0006-291X (Print) 0006-291X (Linking) |
| Abstract: | "We have isolated two distinct pheromone-biosynthesis-activating neuropeptides (PBAN), named PBAN-I and -II, as fully oxidized forms of Met residues from adult heads of the silkworm, Bombyx mori. PBAN-I was identical with the PBAN which we had isolated before. The complete amino acid sequence of PBAN-I, a total of 33 amino acid residues, was determined as H-Leu-Ser-Glu-Asp-Met-Pro-Ala-Thr-Pro-Ala-Asp-Gln-Glu-Met-Tyr-Gln-Pro-As p-Pro- Glu-Glu-Met-Glu-Ser-Arg-Thr-Arg-Tyr-Phe-Ser-Pro-Arg-Leu-NH2. Synthetic PBAN-I after oxidation with H2O2 was chromatographically identical with the isolated PBAN-I. Examination of PBAN activity of synthetic analogues indicated that the carboxyl-terminal portion of PBAN-I was important for biological activity" |
| Keywords: | "Amino Acid Sequence Animals Bombyx/*analysis Chromatography, High Pressure Liquid Molecular Sequence Data Neuropeptides/*analysis/isolation & purification/pharmacology Pheromones/*metabolism Sex Attractants/*metabolism Structure-Activity Relationship;" |
| Notes: | "MedlineKitamura, A Nagasawa, H Kataoka, H Inoue, T Matsumoto, S Ando, T Suzuki, A eng Research Support, Non-U.S. Gov't 1989/08/30 Biochem Biophys Res Commun. 1989 Aug 30; 163(1):520-6. doi: 10.1016/0006-291x(89)92168-2" |
