| Title: | [Non-specific adherence of Enterococcus faecalis strains isolated from healthy voluntaries and infection of urinary tract] |
| Author(s): | Jarzembowski T; Dabrowska-Szponar M; |
| Address: | Zaklad Mikrobiologii Lekarskiej Katedra Mikrobiologii Akademii Medycznej w Gdansku |
| ISSN/ISBN: | 0025-8601 (Print) 0025-8601 (Linking) |
| Abstract: | "Enterococcus faecalis is a component of human and animal gastrointestinal microflora. However, the adhesion is considered to be the key step in the pathogenesis of enterococcal infections and the first step of biofilm formation. We aimed to compare and evaluate adherence of strains considered to be commensal flora (isolated from healthy volunteers) and strains isolated as a pathogen from medical samples in Gdansk Region The additional aim of this study was to analyze influence of subinhibitory concentration of gentamycin and cAD1 pheromone. Comparison involved 20 strains isolated from healthy voluntaries, 23 strains isolated as etiological agent of urinary tract infection and 16 HLAR strains from other infections. Adherence ability was tasted by turbidymetric method at 550 nm, as o reduction of bacterial inoculum after incubation with hydroksyapatite. Results showed significant difference between commensal and virulent strains as well as between none-inducted and inducted by pheromone. In contrast there was no difference between inducted and non-inducted virulent strains as well as between inducted virulent and inducted not virulent strains. The result shows ability to differentiate this group by non-specific adherence" |
| Keywords: | Bacterial Adhesion/drug effects/*physiology Bacterial Proteins/pharmacology Biofilms/drug effects Durapatite/chemistry Enterococcus faecalis/drug effects/isolation & purification/pathogenicity/*physiology Feces/*microbiology Gentamicins/pharmacology Human; |
| Notes: | "MedlineJarzembowski, Tomasz Dabrowska-Szponar, Maria pol Comparative Study English Abstract Poland 2007/12/15 Med Dosw Mikrobiol. 2007; 59(3):217-22" |
