Title: | Molecular neurobiology of Drosophila taste |
Address: | "Bioengineering Interdepartmental Graduate Program, University of California, Riverside, CA 92521, USA. Bioengineering Interdepartmental Graduate Program, University of California, Riverside, CA 92521, USA; Department of Entomology, University of California, Riverside, CA 92521, USA. Electronic address: anupama.dahanukar@ucr.edu" |
DOI: | 10.1016/j.conb.2015.06.001 |
ISSN/ISBN: | 1873-6882 (Electronic) 0959-4388 (Print) 0959-4388 (Linking) |
Abstract: | "Drosophila is a powerful model in which to study the molecular and cellular basis of taste coding. Flies sense tastants via populations of taste neurons that are activated by compounds of distinct categories. The past few years have borne witness to studies that define the properties of taste neurons, identifying functionally distinct classes of sweet and bitter taste neurons that express unique subsets of gustatory receptor (Gr) genes, as well as water, salt, and pheromone sensing neurons that express members of the pickpocket (ppk) or ionotropic receptor (Ir) families. There has also been significant progress in terms of understanding how tastant information is processed and conveyed to higher brain centers, and modulated by prior dietary experience or starvation" |
Keywords: | "Animals Animals, Genetically Modified Drosophila/cytology/*physiology Drosophila Proteins/genetics *Neurobiology Signal Transduction/*genetics Taste/*genetics;" |
Notes: | "MedlineFreeman, Erica Gene Dahanukar, Anupama eng R01 DC013587/DC/NIDCD NIH HHS/ R21 DC012408/DC/NIDCD NIH HHS/ R01DC013587/DC/NIDCD NIH HHS/ R21DC012408/DC/NIDCD NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review England 2015/06/24 Curr Opin Neurobiol. 2015 Oct; 34:140-8. doi: 10.1016/j.conb.2015.06.001. Epub 2015 Jun 21" |