« Previous AbstractDeciphering the Biotic and Climatic Factors That Influence Floral Scents: A Systematic Review of Floral Volatile Emissions    Next AbstractMale and female developmental temperature modulate post-copulatory interactions in a beetle »

J Insect Sci

Title:		"Insect PRXamides: Evolutionary Divergence, Novelty, and Loss in a Conserved Neuropeptide System"
Author(s):		Farris SM;
Address:		"Department of Biology, West Virginia University, 3139 Life Sciences Building, 53 Campus Drive, Morgantown, WV, USA"
Journal Title:		J Insect Sci
Year:		2023
Volume:		23
Issue:		1
Page Number:		-
DOI:		10.1093/jisesa/ieac079
ISSN/ISBN:		1536-2442 (Electronic) 1536-2442 (Linking)
Abstract:		"The PRXamide neuropeptides have been described in both protostome and deuterostome species, including all major groups of the Panarthropoda. Best studied are the insect PRXamides consisting of three genes: pk/pban, capa, and eth, each encoding multiple short peptides that are cleaved post-translationally. Comparisons of genome and transcriptome sequences reveal that while retaining its fundamental ancestral organization, the products of the pk/pban gene have undergone significant change in the insect Order Diptera. Basal dipteran pk/pban genes are much like those of other holometabolous insects, while more crown species have lost two peptide coding sequences including the otherwise ubiquitous pheromone biosynthesis activating neuropeptide (PBAN). In the genomic model species Drosophila melanogaster, one of the remaining peptides (hugin) plays a potentially novel role in feeding and locomotor regulation tied to circadian rhythms. Comparison of peptide coding sequences of pk/pban across the Diptera pinpoints the acquisition or loss of the hugin and PBAN peptide sequences respectively, and provides clues to associated changes in life history, physiology, and/or behavior. Interestingly, the neural circuitry underlying pk/pban function is highly conserved across the insects regardless of the composition of the pk/pban gene. The rapid evolution and diversification of the Diptera provide many instances of adaptive novelties from genes to behavior that can be placed in the context of emerging selective pressures at key points in their phylogeny; further study of changing functional roles of pk/pban may then be facilitated by the high-resolution genetic tools available in Drosophila melanogaster"
Keywords:		Animals Drosophila melanogaster/genetics *Neuropeptides/genetics/chemistry Insecta/genetics Peptides *Moths/genetics *Drosophila Proteins capa diapause hormone diptera hugin pheromone biosynthesis activating protein;
Notes:		"MedlineFarris, Sarah M eng 2023/01/21 J Insect Sci. 2023 Jan 1; 23(1):3. doi: 10.1093/jisesa/ieac079"