Bedoukian   RussellIPM   RussellIPM   Piezoelectric Micro-Sprayer


Home
Animal Taxa
Plant Taxa
Semiochemicals
Floral Compounds
Semiochemical Detail
Semiochemicals & Taxa
Synthesis
Control
Invasive spp.
References

Abstract

Guide

Alphascents
Pherobio
InsectScience
E-Econex
Counterpart-Semiochemicals
Print
Email to a Friend
Kindly Donate for The Pherobase

« Previous AbstractChemical composition of essential oils of eight Tunisian Eucalyptus species and their antibacterial activity against strains responsible for otitis    Next AbstractGreen leaf volatile production by plants: a meta-analysis »

Open Microbiol J


Title:In vitro Antibacterial Activity and Phytochemical Analysis of Nicotiana tabacum L. Extracted in Different Organic Solvents
Author(s):Ameya G; Manilal A; Merdekios B;
Address:"Department of Medical Laboratory Science, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia. Department of Public Health, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia"
Journal Title:Open Microbiol J
Year:2017
Volume:20171229
Issue:
Page Number:352 - 359
DOI: 10.2174/1874285801711010352
ISSN/ISBN:1874-2858 (Print) 1874-2858 (Electronic) 1874-2858 (Linking)
Abstract:"BACKGROUND: Controlling infectious disease using medicinal plants is the oldest healthcare known to mankind. Regardless of the enormous advances observed in modern medicine, medicinal plants are still playing vital roles. However, only a small proportion of medicinal plants are examined for bioactive compounds which may vary in different factors. This study aimed to evaluate phytochemical constituent and antimicrobial activities of Nicotiana tabacum L. extracted by different solvents against three set of bacteria. METHODS: Nicotiana tabacum L. was collected from the Western Ethiopia and extracted in seven organic solvents. An in-vitro anti-bacterial activity of plant extracts was carried out by agar well diffusion assay against microbial type culture collection of human pathogens, clinical bacterial isolates, and biofilm forming bacteria. Gas Chromatographic and Mass Spectroscopic (GC-MS) analysis was used to determine the phytochemical constituents. RESULTS: Antimicrobial activities of plant extract vary by extraction solvents; and ethyl acetate based extracts showed better antimicrobial activities. Of the experimental organisms, biofilm forming uropathogens were the most sensitive while clinical isolates were quite resistant. Analysis of the active ethyl acetate extract by GC-MS evinced a mixture of five volatile compounds; and Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S) was the major compound detected. The overall results of the present study revealed that N. tabacum L extract has high antimicrobial activities against biofilm forming uropathogens. CONCLUSION: High antimicrobial activity was observed in ethyl acetate extract of N. tabacum against the biofilm forming bacteria whereas the clinically isolated bacteria were the most resistant group. The antibacterial property demonstrated could be due to Pyridine, 3-(1-methyl-2-pyrrolidinyl)-(S) with a broad spectrum of activity"
Keywords:Antibacterial activity Antibacterial property Nicotiana tabacum L Phytochemical analysis Plant extract Spectrum;
Notes:"PubMed-not-MEDLINEAmeya, Gemechu Manilal, Aseer Merdekios, Behailu eng United Arab Emirates 2018/02/06 Open Microbiol J. 2017 Dec 29; 11:352-359. doi: 10.2174/1874285801711010352. eCollection 2017"

 
Back to top
 
Citation: El-Sayed AM 2024. The Pherobase: Database of Pheromones and Semiochemicals. <http://www.pherobase.com>.
© 2003-2024 The Pherobase - Extensive Database of Pheromones and Semiochemicals. Ashraf M. El-Sayed.
Page created on 16-11-2024