| Title: | "Composition and Antioxidant, Antienzymatic and Antimicrobial Activities of Volatile Molecules from Spanish Salvia lavandulifolia (Vahl) Essential Oils" |
| Author(s): | Cutillas AB; Carrasco A; Martinez-Gutierrez R; Tomas V; Tudela J; |
| Address: | "GENZ-Group of Research on Enzymology, Department of Biochemistry and Molecular Biology-A, Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain. anabelen.cutillas@um.es. GENZ-Group of Research on Enzymology, Department of Biochemistry and Molecular Biology-A, Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain. alejandro.carrasco@um.es. Novozymes Spain S.A., 28224 Madrid, Spain. rma@novozymes.com. Department of Analytical Chemistry, University of Murcia, 30100 Murcia, Spain. virginia@um.es. GENZ-Group of Research on Enzymology, Department of Biochemistry and Molecular Biology-A, Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain. tudelaj@um.es" |
| DOI: | 10.3390/molecules22081382 |
| ISSN/ISBN: | 1420-3049 (Electronic) 1420-3049 (Linking) |
| Abstract: | "The current study describes the composition of Salvia lavandulifolia (Vahl) essential oils (SlEOs) obtained from plants cultivated in Murcia (Spain), as determined by gas chromatography. Relative and absolute concentrations, the enantiomeric ratios of chiral compounds and the in vitro antioxidant, antienzymatic and antimicrobial activities are described. The main components of the SlEOs were camphor, 1,8-cineole, camphene and alpha-pinene, and the main enantiomers were (+)-camphor and (-)-camphene. The activities against free radicals and the capacity to reduce and chelate metallic ions were measured. SlEO-3 showed the highest activity in ORAC, DPPH, ABTS and reducing power methods, while SlEO-1 exhibited the highest chelating power. The activity of lipoxygenase and acetylcholinesterase could be inhibited by all the SlEOs, being bornyl acetate and limonene the most active individual compounds against lipoxygenase and 1,8-cineole against acetylcholinesterase. SlEOs and some individual compounds inhibited Escherichia coli, Staphylococcus aureus and Candida albicans. These results increase our knowledge of SlEOs and, particularly, provide for the first time a complete characterization of SlEOs from Murcia, Spain, while proposing possible biotechnological uses for them" |
| Keywords: | "Anti-Infective Agents/*chemistry/pharmacology Antioxidants/*chemistry/pharmacology Bacteria/drug effects Enzyme Inhibitors/*chemistry/pharmacology Fungi/drug effects Gas Chromatography-Mass Spectrometry Microbial Sensitivity Tests Oils, Volatile/*chemistr;" |
| Notes: | "MedlineCutillas, Ana-Belen Carrasco, Alejandro Martinez-Gutierrez, Ramiro Tomas, Virginia Tudela, Jose eng Switzerland 2017/08/22 Molecules. 2017 Aug 21; 22(8):1382. doi: 10.3390/molecules22081382" |
