| Title: | "Evaluation of several novel alkynols, alkenols, and selected host odor blends as attractants to female Aedes albopictus and Culex quinquefasciatus" |
| Author(s): | Cilek JE; Ikediobi CO; Hallmon CF; Johnson R; Okungbowa O; Onyeozili EN; Khalil LM; Ayuk-Takem L; Latinwo LM; Bernier UR; |
| Address: | "John A. Mulrennan, Sr. Public Health Entomology Research and Education Center, College of Engineering Sciences, Technology and Agriculture, Florida A&M University, 4000 Frankford Avenue, Panama City, FL 32405, USA" |
| ISSN/ISBN: | 8756-971X (Print) 8756-971X (Linking) |
| Abstract: | "The compound 1-octen-3-ol is a strong attractant for some mosquito species. Based on chemical structure, this may be due to a terminal site of unsaturation or high electron density, a structural capability for hydrogen bonding, e.g., -OH, -NH2, NHR, NR2, etc., a saturated hydrocarbon chain of a certain minimum length, and a certain relative distance between the region of high electron density and the alcohol (or other hydrogen-bonding) functional group. Based on this hypothesis, 4 novel alkynol (triple-bonded) analogs were synthesized and evaluated alone or in combination with acetone and dimethyl disulfide, and with and without carbon dioxide in Mosquito Magnet-X suction traps. Attraction of laboratory-reared adult Aedes albopictus and Culex quinquefasciatus to these analogs and combinations was compared to 1-octen-3-ol as a standard in semi-field trials. For both species none of the alkynols, with and without carbon dioxide or acetone and dimethyl disulfide, were significantly different from 1-octen-3-ol. The compounds 2-octyn-4-ol and 2-nonyn-4-ol alone and with carbon dioxide suppressed Cx. quinquefasciatus collections. An additional 6 alkenol (double-bonded) analogs were tested in mixtures with 3-n-propylphenol and 4-methylphenol in a ratio of 4:1:8, respectively. Using the same trapping methods, Cx. quinquefasciatus catches containing 3-decen-1-ol were increased nearly 3-fold when combined with carbon dioxide. Aedes albopictus collections in traps with the 3-decen-1-ol/phenol mixture and carbon dioxide were significantly greater than similar traps with 1-octen-3-ol. Traps baited with the phenol blends that incorporated (Z)-3-nonen-1-ol, (Z)-8-nonen-3-ol, or 1-octen-3-ol were considerably suppressed in the presence of carbon dioxide" |
| Keywords: | "Aedes/*drug effects Alcohols/chemistry/*pharmacology Animals Behavior, Animal/*drug effects Biological Assay Culex/*drug effects Female Molecular Structure Pheromones/chemistry/*pharmacology;" |
| Notes: | "MedlineCilek, J E Ikediobi, C O Hallmon, C F Johnson, R Okungbowa, O Onyeozili, E N Khalil, L M Ayuk-Takem, L Latinwo, L M Bernier, U R eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. 2013/07/10 J Am Mosq Control Assoc. 2012 Sep; 28(3):199-205. doi: 10.2987/12-6226R.1" |
