| Title: | "Screening of degradation products, impurities and precursors of chemical warfare agents in water and wet or dry organic liquid samples by in-sorbent tube silylation followed by thermal desorption-gas chromatography-mass spectrometry" |
| Address: | "Organisation for the Prohibition of Chemical Weapons, Inspectorate Division, Johan de Wittlaan 32, 2517 JR The Hague, The Netherlands. oterzic@gmail.com" |
| DOI: | 10.1016/j.chroma.2010.05.042 |
| ISSN/ISBN: | 1873-3778 (Electronic) 0021-9673 (Linking) |
| Abstract: | "A standard method used by inspection teams of the Organisation for the Prohibition of Chemical Weapons (OPCW) for preparation of aqueous samples requires several extraction and derivatization steps. This results in tedious and time consuming on-site analysis. A simple thermal desorption-gas chromatography-mass spectrometry (TD-GC-MS) method was developed to analyse for a broad range of degradation products, impurities and precursors of chemical warfare agents (CWA) in water solutions and wet or dry organic liquid samples. The method is fast, sensitive, requires only microliter volumes of sample and enables the simultaneous determination of a wide range of compounds with widely differing polarity, volatility and reactivity. The applicability of the method was demonstrated by successful analysis of five OPCW Official Proficiency Test samples" |
| Keywords: | "Chemical Warfare Agents/*chemistry Gas Chromatography-Mass Spectrometry/*methods Organic Chemicals/analysis Water Pollutants, Chemical/*chemistry;" |
| Notes: | "MedlineTerzic, Oliver eng Evaluation Study Netherlands 2010/06/15 J Chromatogr A. 2010 Jul 23; 1217(30):4987-95. doi: 10.1016/j.chroma.2010.05.042. Epub 2010 May 31" |
