Title: | "Transcriptional control of SSL1, a gene controlling alpha-specific inactivation of a-factor in Saccharomyces cerevisiae" |
Address: | "Institut fur Physiologische Chemie, Ruhr-Universitat Bochum, F.R.G" |
DOI: | 10.1016/s0378-1097(05)80045-x |
ISSN/ISBN: | 0378-1097 (Print) 0378-1097 (Linking) |
Abstract: | The SSL1 gene of S. cerevisiae which is involved in the cell-type specific recovery of mating type alpha cells from cell cycle arrest by the mating hormone a-factor has been cloned as a 1 kb Sau3A fragment in a complementing plasmid from a library of S. cerevisae genomic DNA. Disruption of this gene in wild-type alpha-cells results in the ssl1- phenotype which is characterized by an extreme sensitivity to a-factor. Transcription analysis revealed that the SSL1 gene is transcribed only in MAT alpha cells but not in MAT alpha or diploid (MAT alpha/MAT alpha) cells defining it as a member of the set of alpha-specific genes |
Keywords: | "Blotting, Southern *Gene Expression Regulation, Fungal *Genes, Fungal *Genes, Mating Type, Fungal Genes, Regulator Mating Factor Peptides/*genetics Restriction Mapping Saccharomyces cerevisiae/*genetics *Transcription, Genetic;" |
Notes: | "MedlineSteden, M Duntze, W eng Research Support, Non-U.S. Gov't England 1990/03/15 FEMS Microbiol Lett. 1990 Mar 15; 56(3):229-32. doi: 10.1016/s0378-1097(05)80045-x" |