| Title: | "Total polyphenolic compounds, total flavonoids, GC-MS analysis of volatile constituents, evaluation of antioxidant and antimicrobial activities of Prunus dulcis nuts" |
| Author(s): | Qureshi MN; Numonov S; Aisa HA; |
| Address: | "Department of Chemistry, University of Swabi, Swabi, Pakistan/Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan/Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, PR China. Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, PR China/Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, P. R. China/State Scientifically-Experimental and Production Organization Academy of Sciences of the Republic of Tajikistan, Dushanbe, Tajikistan. Key Laboratory of Plant Resources and Chemistry in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, PR China/Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, P. R. China" |
| ISSN/ISBN: | 1011-601X (Print) 1011-601X (Linking) |
| Abstract: | "Prunus dulcis has been known as a source of nutrients in many traditional foods and as a source of important biologically active compounds in traditional medicines. The present study describes the determination of total polyphenolic compounds, total flavonoids and GC-MS analysis of hexane and chloroform fractions of 70% ethanol extract of whole almond shelled seed. Antioxidant and antimicrobial activities of various extracts of the nuts were evaluated. Folin-Ciocalteau procedure resulted in total polyphenolic compounds as 0.008 mg (gallic acid equivalents)/mg of the dried extract and amount of total flavonoids contents yielded were 0.001 mg (quercetin equivalents)/mg of the nuts dried extracts. GC-MS analysis of the hexane and chloroform fractions yielded a number of volatile constituents, resulting in highest amounts of 6-Octadecenoic acid and 1,1,3,3-Tetramethyl cyclopentane as 37.52% and 24.54% in hexane and chloroform fractions respectively. Antioxidant activity using the DPPH radical scavenging assay resulted in very low activity in all the extracts. Only n-butanol extract showed mild activity against the gram negative E. coli with inhibition zone diameter 8 mm while rest of samples did not show any activity against any microbial strains under study" |
| Keywords: | "Anti-Infective Agents/chemistry/*pharmacology Antioxidants/chemistry/*pharmacology Drug Evaluation, Preclinical Flavonoids/*analysis Gas Chromatography-Mass Spectrometry Microbial Sensitivity Tests Nuts/chemistry Plant Extracts/analysis/chemistry/pharmaco;" |
| Notes: | "MedlineQureshi, Muhammad Nasimullah Numonov, Sodik Aisa, Haji Akber eng Pakistan 2019/10/15 Pak J Pharm Sci. 2019 Jul; 32(4):1461-1466" |
