Title: | Utilization of road dust chemical profiles for source identification and human health impact assessment |
Address: | "Chemical Safety Research Center, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea. eakim@nafi.re.kr. National Assembly Futures Institute, Members Office Bldg, 1 Uisadang-daero, Yeongdeungpo-gu, Seoul, 07233, Republic of Korea. eakim@nafi.re.kr. Bio Platform Technology Research Center, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea. bkoh@krict.re.kr" |
DOI: | 10.1038/s41598-020-71180-x |
ISSN/ISBN: | 2045-2322 (Electronic) 2045-2322 (Linking) |
Abstract: | "This study investigated the chemical profiles of fine urban road dust as a set of indicators for major air pollutants at sampling sites or as proxies for potential human health impacts. We examined the chemical compositions of fine particles (< 100 mum) or re-suspended ultrafine particles (< 2.5 mum) in the urban road dust collected from the cities with major emission sources of CO, NH(3), NO(x), PM(2.5), SO(x), and volatile organic compounds. The elemental compositions, including metal contents and volatile or semi-volatile organic compound species were determined to constitute comprehensive chemical profiles of the solid road dust samples. The water-extractable organic compounds and fluorescent species of the size-fractionated re-suspended fine particulate matter (RPM) were also incorporated in the chemical profiles. The metal content and aliphatic hydrocarbons could partly distinguish emission sources, and clearer distinctions were achieved with the inclusion of fluorescence excitation-emission matrix (EEM) results. The dose-response test results showed positive correlations between cytotoxicity and relative abundance of hydrocarbons or metal contents of urban road dust. The set of chemical profiles suggested in this study could be further utilized for site identification or human health impact assessment using urban road dust" |
Keywords: | "Dose-Response Relationship, Drug Dust/*analysis Fibroblasts/drug effects Health Impact Assessment Humans Hydrocarbons/adverse effects/analysis Lung/cytology/drug effects Metals/adverse effects/analysis Particle Size Particulate Matter/adverse effects/*ana;" |
Notes: | "MedlineKim, Eun-Ah Koh, Byumseok eng Research Support, Non-U.S. Gov't England 2020/09/02 Sci Rep. 2020 Aug 31; 10(1):14259. doi: 10.1038/s41598-020-71180-x" |