« Previous Abstract"Pheromone may induce brood tending in the fire ant, Solenopsis saevissima"    Next AbstractVariability of personal chemical exposure in eight office buildings in Sweden »

Chem Phys Lipids

Title:		Strategies for the chemoenzymatic preparation of optically active 1-alkyn-3-ols
Author(s):		Glanzer BI; Konigsberger K; Berger B; Faber K; Griengl H;
Address:		"Institute of Organic Chemistry, Graz University of Technology, Austria"
Journal Title:		Chem Phys Lipids
Year:		1990
Volume:		54
Issue:		1
Page Number:		43 - 48
DOI:		10.1016/0009-3084(90)90058-y
ISSN/ISBN:		0009-3084 (Print) 0009-3084 (Linking)
Abstract:		"A series of (R)- and (S)-1-alkyn-3-ols, chiral building units for the synthesis of leukotrienes and pheromones, were prepared via enantioselective hydrolysis of their racemic esters. While the majority of biocatalysts employed (lipases, fermenting or freeze-dried microorganisms) failed in discriminating between enantiomers, lyophilized cells of baker's yeast (Saccharomyces cerevisiae Hansen) gave (S)-1-alkyn-3-ols and their corresponding (R)-esters with greater than 90% e.e"
Keywords:		Alcohols/*chemical synthesis Alkynes/*chemical synthesis Bacillus subtilis Brevibacterium Chemical Phenomena Chemistry Enzymes Lipase Optical Rotation Rhizopus Saccharomyces cerevisiae;
Notes:		"MedlineGlanzer, B I Konigsberger, K Berger, B Faber, K Griengl, H eng Research Support, Non-U.S. Gov't Ireland 1990/04/01 Chem Phys Lipids. 1990 Apr; 54(1):43-8. doi: 10.1016/0009-3084(90)90058-y"