| Title: | Halogenated Organic Pollutant Residuals in Human Bared and Clothing-Covered Skin Areas: Source Differentiation and Comprehensive Health Risk Assessment |
| Author(s): | Cao Z; Chen Q; Zhu C; Chen X; Wang N; Zou W; Zhang X; Zhu G; Li J; Mai B; Luo X; |
| Address: | "School of Environment, Key Laboratory for Yellow River and Huai River Water Environment and Pollution Control, Ministry of Education , Henan Normal University , Xinxiang 453007 , China. Beijing Key Laboratory for Emerging Organic Contaminants Control , Tsinghua University , Beijing 100084 , China. State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry , Chinese Academy of Sciences , Guangzhou 510640 , China" |
| ISSN/ISBN: | 1520-5851 (Electronic) 0013-936X (Linking) |
| Abstract: | "To comprehensively clarify human exposure to halogenated flame retardants (HFRs) and polychlorinated biphenyls (PCBs) through dermal uptake and hand-to-mouth intake, skin wipe samples from four typical skin locations from 30 volunteers were collected. The total concentration of the target chemicals (24 HFRs and 16 PCBs) ranged from 203 to 4470 ng/m(2). BDE-209 and DBDPE accounted for about 37 and 40% of summation operator(24)HFRs, respectively, and PCB-41 and PCB-110 were the dominant PCB congeners, with proportion of 24 and 10%, respectively. Although exhibiting relatively lower concentrations of contaminants than bared skin locations, clothing-covered skin areas were also detected with considerable levels of HFRs and PCBs, indicating clothing to be a potentially significant exposure source. Significant differences in HFR and PCB levels and profiles were also observed between males and females, with more lower-volatility chemicals in male-bared skin locations and more higher-volatility compounds in clothing-covered skin locations of female participants. The mean estimated whole-body dermal absorption doses of summation operator(8)HFRs and summation operator(16)PCBs (2.9 x 10(-4) and 6.7 x 10(-6) mg/kg.d) were 1-2 orders of magnitude higher than ingestion doses via hand-to-mouth contact (6.6 x 10(-7) and 3.1 x 10(-7) mg/kg.d). The total noncarcinogenic health risk resulted from whole-body dermal absorption and oral ingestion to summation operator(7)HFRs and summation operator(16)PCBs were 5.2 and 0.35, respectively" |
| Keywords: | Clothing Environmental Monitoring *Environmental Pollutants Female *Flame Retardants Halogenated Diphenyl Ethers Humans Male *Polychlorinated Biphenyls Risk Assessment; |
| Notes: | "MedlineCao, Zhiguo Chen, Qiaoying Zhu, Chunyou Chen, Xi Wang, Neng Zou, Wei Zhang, Xingli Zhu, Guifen Li, Jinghua Mai, Bixian Luo, Xiaojun eng Research Support, Non-U.S. Gov't 2019/10/22 Environ Sci Technol. 2019 Dec 17; 53(24):14700-14708. doi: 10.1021/acs.est.9b04757. Epub 2019 Oct 29" |
